Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant.
about
Conserved allosteric hot spots in the transmembrane domains of cystic fibrosis transmembrane conductance regulator (CFTR) channels and multidrug resistance protein (MRP) pumps.Cystic fibrosis transmembrane conductance regulator chloride channel blockers: Pharmacological, biophysical and physiological relevance.Modeling the conformational changes underlying channel opening in CFTRLocalizing a gate in CFTR.Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics.Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7).Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore.Molecular modelling and molecular dynamics of CFTR.The CFTR ion channel: gating, regulation, and anion permeationCysteine scanning of CFTR's first transmembrane segment reveals its plausible roles in gating and permeationSpatial positioning of CFTR's pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathwayNonequilibrium gating of CFTR on an equilibrium theme.Functional architecture of the CFTR chloride channel.Conformational changes opening and closing the CFTR chloride channel: insights from cysteine scanning mutagenesis.Cytoplasmic pathway followed by chloride ions to enter the CFTR channel pore.Structural Changes Fundamental to Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Pore.Functional Architecture of the Cytoplasmic Entrance to the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore.Architecture and functional properties of the CFTR channel pore.Tuning of CFTR chloride channel function by location of positive charges within the pore.Relative movements of transmembrane regions at the outer mouth of the cystic fibrosis transmembrane conductance regulator channel pore during channel gatingRole of the juxtamembrane region of cytoplasmic loop 3 in the gating and conductance of the cystic fibrosis transmembrane conductance regulator chloride channel.Alternating access to the transmembrane domain of the ATP-binding cassette protein cystic fibrosis transmembrane conductance regulator (ABCC7).Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): CLOSED AND OPEN STATE CHANNEL MODELS.Metal bridges illuminate transmembrane domain movements during gating of the cystic fibrosis transmembrane conductance regulator chloride channel.Relative contribution of different transmembrane segments to the CFTR chloride channel pore.Stoichiometry and novel gating mechanism within the cystic fibrosis transmembrane conductance regulator channel.Structural mechanisms of CFTR function and dysfunction.
P2860
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P2860
Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Functional arrangement of the ...... a cysteine-less CFTR variant.
@en
Functional arrangement of the ...... a cysteine-less CFTR variant.
@nl
type
label
Functional arrangement of the ...... a cysteine-less CFTR variant.
@en
Functional arrangement of the ...... a cysteine-less CFTR variant.
@nl
prefLabel
Functional arrangement of the ...... a cysteine-less CFTR variant.
@en
Functional arrangement of the ...... a cysteine-less CFTR variant.
@nl
P2860
P1433
P1476
Functional arrangement of the ...... a cysteine-less CFTR variant.
@en
P2093
Yassine El Hiani
P2860
P2888
P304
P356
10.1007/S00424-011-0998-2
P577
2011-07-28T00:00:00Z