Identification of target genes for the CDK subunits of the Mediator complex.
about
Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast CancerMediator kinase module and human tumorigenesisDiscovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.The Mediator complex and transcription regulationMediator subunit Med12 contributes to the maintenance of neural stem cell identity.Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genesRegulation of metabolism by the Mediator complex.miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cellsMediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9.Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.A CDK2 activity signature predicts outcome in CDK2-low cancers.Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila.Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure.Mediator MED18 subunit plays a negative role in transcription via the CDK/cyclin module.Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of Cyclin C-CDK8/19.Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries.
P2860
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P2860
Identification of target genes for the CDK subunits of the Mediator complex.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
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2011年學術文章
@zh-hant
name
Identification of target genes for the CDK subunits of the Mediator complex.
@en
Identification of target genes for the CDK subunits of the Mediator complex.
@nl
type
label
Identification of target genes for the CDK subunits of the Mediator complex.
@en
Identification of target genes for the CDK subunits of the Mediator complex.
@nl
prefLabel
Identification of target genes for the CDK subunits of the Mediator complex.
@en
Identification of target genes for the CDK subunits of the Mediator complex.
@nl
P2093
P2860
P1433
P1476
Identification of target genes for the CDK subunits of the Mediator complex.
@en
P2093
Aki Tanaka
Rikiya Fukasawa
Taiki Tsutsui
Yoshiaki Ohkuma
Yutaka Hirose
P2860
P304
P356
10.1111/J.1365-2443.2011.01565.X
P577
2011-11-27T00:00:00Z