Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex.
about
Drf1, a novel regulatory subunit for human Cdc7 kinaseHuman cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication.An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing.Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen speciesNonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosisTranscriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activityCDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 proteinA Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replicationThree wise centromere functions: see no error, hear no break, speak no delayApplication of a new dual localization-affinity purification tag reveals novel aspects of protein kinase biology in Aspergillus nidulansSaccharomyces cerevisiae Dbf4 Has Unique Fold Necessary for Interaction with Rad53 KinaseCdc7p-Dbf4p regulates mitotic exit by inhibiting Polo kinase.The mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae.A novel destruction sequence targets the meiotic regulator Spo13 for anaphase-promoting complex-dependent degradation in anaphase I.Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complexKinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment.Mechanisms Governing DDK Regulation of the Initiation of DNA ReplicationHuman Dbf4/ASK promoter is activated through the Sp1 and MluI cell-cycle box (MCB) transcription elementsThe potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffoldsA quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations.CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.Multiple regulatory mechanisms to inhibit untimely initiation of DNA replication are important for stable genome maintenance.A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.Ubiquitin-mediated proteolysis of vertebrate G1- and S-phase regulators.The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20pCdc7 kinase complex: a key regulator in the initiation of DNA replication.Characterization of a Drosophila ortholog of the Cdc7 kinase: a role for Cdc7 in endoreplication independent of Chiffon.The spindle checkpoint protein Mad2 regulates APC/C activity during prometaphase and metaphase of meiosis I in Saccharomyces cerevisiae.Eukaryotic MCM proteins: beyond replication initiation.Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis.Cyclin-specific control of ribosomal DNA segregationDbf4: the whole is greater than the sum of its partsChromosome Duplication in Saccharomyces cerevisiae.Helicase activation and establishment of replication forks at chromosomal origins of replication.Budding yeast Dbf4 sequences required for Cdc7 kinase activation and identification of a functional relationship between the Dbf4 and Rev1 BRCT domainsDbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosisRoles of CDK and DDK in Genome Duplication and Maintenance: Meiotic Singularities.Processive ubiquitin chain formation by the anaphase-promoting complex.
P2860
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P2860
Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
Dbf4p, an essential S phase-pr ...... he anaphase-promoting complex.
@en
Dbf4p, an essential S phase-pr ...... he anaphase-promoting complex.
@nl
type
label
Dbf4p, an essential S phase-pr ...... he anaphase-promoting complex.
@en
Dbf4p, an essential S phase-pr ...... he anaphase-promoting complex.
@nl
prefLabel
Dbf4p, an essential S phase-pr ...... he anaphase-promoting complex.
@en
Dbf4p, an essential S phase-pr ...... he anaphase-promoting complex.
@nl
P2860
P1476
Dbf4p, an essential S phase-pr ...... he anaphase-promoting complex.
@en
P2093
M F Ferreira
P2860
P304
P356
10.1128/MCB.20.1.242-248.2000
P407
P577
2000-01-01T00:00:00Z