Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
about
A novel function of novobiocin: disrupting the interaction of HIF 1α and p300/CBP through direct binding to the HIF1α C-terminal activation domain.Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors.KU-32, a novel drug for diabetic neuropathy, is safe for human islets and improves in vitro insulin secretion and viability.Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors.Alternative approaches to Hsp90 modulation for the treatment of cancer.Novobiocin Analogues That Inhibit the MAPK Pathway.
P2860
Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
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2011年學術文章
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name
Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
@en
Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
@nl
type
label
Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
@en
Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
@nl
prefLabel
Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
@en
Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
@nl
P2093
P2860
P1476
Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors.
@en
P2093
Adam S Duerfeldt
Bhaskar Reddy Kusuma
Brian S J Blagg
P2860
P304
P356
10.1016/J.BMCL.2011.09.073
P407
P577
2011-10-01T00:00:00Z