Interaction between DNA gyrase and quinolones: effects of alanine mutations at GyrA subunit residues Ser(83) and Asp(87).
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Evolution of drug resistance in tuberculosis: recent progress and implications for diagnosis and therapyMycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activityPlasmid-mediated quinolone resistance in Enterobacteriaceae: a systematic review with a focus on Mediterranean countries.Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase.Increasing Macrolide and Fluoroquinolone Resistance in Mycoplasma genitaliumThe structural modeling of the interaction between levofloxacin and the Mycobacterium tuberculosis gyrase catalytic site sheds light on the mechanisms of fluoroquinolones resistant tuberculosis in Colombian clinical isolates.Anti-tubercular drug designing by structure based screening of combinatorial libraries.Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure.High genetic diversity of ciprofloxacin-nonsusceptible isolates of Streptococcus pneumoniae in Poland.A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis.Combinatorially-generated library of 6-fluoroquinolone analogs as potential novel antitubercular agents: a chemometric and molecular modeling assessment.Role of the extended alpha4 domain of Staphylococcus aureus gyrase A protein in determining low sensitivity to quinolones.Topoisomerase targeting with and resistance to gemifloxacin in Staphylococcus aureusClinical importance and epidemiology of quinolone resistance.The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibilityAnalysis of the gyrA gene of clinical Yersinia ruckeri isolates with reduced susceptibility to quinolones.Deoxynybomycins inhibit mutant DNA gyrase and rescue mice infected with fluoroquinolone-resistant bacteriaDrug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.Detection of multidrug resistance in Mycobacterium tuberculosisDrug and multidrug resistance among Mycobacterium leprae isolates from Brazilian relapsed leprosy patients.Quinolone resistance and ornithine decarboxylation activity in lactose-negative Escherichia coli.Mechanisms of resistance to quinolones.A fluoroquinolone resistance associated mutation in gyrA Affects DNA supercoiling in Campylobacter jejuniATP-bound conformation of topoisomerase IV: a possible target for quinolones in Streptococcus pneumoniaeFluoroquinolones stimulate the DNA cleavage activity of topoisomerase IV by promoting the binding of Mg(2+) to the second metal binding site.Quinolone-mediated bacterial death.Clinically relevant mutant DNA gyrase alters supercoiling, changes the transcriptome, and confers multidrug resistance.The pentapeptide repeat proteins MfpAMt and QnrB4 exhibit opposite effects on DNA gyrase catalytic reactions and on the ternary gyrase-DNA-quinolone complex.Quinolones: action and resistance updated.Mechanism of quinolone action and resistance.Quinolone-DNA interaction: sequence-dependent binding to single-stranded DNA reflects the interaction within the gyrase-DNA complex.Helicobacter pylori and Antibiotic Resistance, A Continuing and Intractable Problem.Mechanisms of fluoroquinolone resistance in Escherichia coli isolates from food-producing animals.The key DNA-binding residues in the C-terminal domain of Mycobacterium tuberculosis DNA gyrase A subunit (GyrA).Enhancement of fluoroquinolone activity by C-8 halogen and methoxy moieties: action against a gyrase resistance mutant of Mycobacterium smegmatis and a gyrase-topoisomerase IV double mutant of Staphylococcus aureus.Quinolone-binding pocket of DNA gyrase: role of GyrB.Implications of amino acid substitutions in GyrA at position 83 in terms of oxolinic acid resistance in field isolates of Burkholderia glumae, a causal agent of bacterial seedling rot and grain rot of rice.Insights into Pyrazinamidase and DNA Gyrase Protein Structures in Resistant and Susceptible Clinical Isolates of Mycobacterium tuberculosis.Evolution of Cost-Free Resistance under Fluctuating Drug Selection in Pseudomonas aeruginosa.Quantitative contributions of target alteration and decreased drug accumulation to Pseudomonas aeruginosa fluoroquinolone resistance.
P2860
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P2860
Interaction between DNA gyrase and quinolones: effects of alanine mutations at GyrA subunit residues Ser(83) and Asp(87).
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
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2001年學術文章
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name
Interaction between DNA gyrase ...... s at GyrA subunit residues Ser
@nl
Interaction between DNA gyrase ...... residues Ser(83) and Asp(87).
@en
type
label
Interaction between DNA gyrase ...... s at GyrA subunit residues Ser
@nl
Interaction between DNA gyrase ...... residues Ser(83) and Asp(87).
@en
prefLabel
Interaction between DNA gyrase ...... s at GyrA subunit residues Ser
@nl
Interaction between DNA gyrase ...... residues Ser(83) and Asp(87).
@en
P2860
P1476
Interaction between DNA gyrase ...... residues Ser(83) and Asp(87).
@en
P2093
Barnard FM
P2860
P304
P356
10.1128/AAC.45.7.1994-2000.2001
P407
P577
2001-07-01T00:00:00Z