Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. - Wikidata - awgldk - TriplyDB

Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.

Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.

http://www.wikidata.org/entity/Q35682250

about

Fluoroquinolone-gyrase-DNA complexes: two modes of drug binding.Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridge Bypassing fluoroquinolone resistance with quinazolinediones: studies of drug-gyrase-DNA complexes having implications for drug design.Activity of quinolone CP-115,955 against bacterial and human type II topoisomerases is mediated by different interactions.Structure based in silico analysis of quinolone resistance in clinical isolates of Salmonella Typhi from India.Protective effect of Qnr on agents other than quinolones that target DNA gyrase.Mechanisms of drug resistance: quinolone resistance.Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase.Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis.Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance.Suppression of gyrase-mediated resistance by C7 aryl fluoroquinolones.Overcoming target-mediated quinolone resistance in topoisomerase IV by introducing metal-ion-independent drug-enzyme interactions.Mechanism of quinolone action and resistance.Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance.Molecular basis for the differential quinolone susceptibility of mycobacterial DNA gyrase.Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.Antimicrobial susceptibility and the in vitro postantibiotic effects of vancomycin and ciprofloxacin against Bacillus cereus isolates.Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914.Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase.Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance.Activities of gyrase and topoisomerase IV on positively supercoiled DNA.Fluoroquinolone-Gyrase-DNA Cleaved Complexes.A new class of antibacterials, the imidazopyrazinones, reveal structural transitions involved in DNA gyrase poisoning and mechanisms of resistance.Antimicrobial resistance (AMR) nanomachines-mechanisms for fluoroquinolone and glycopeptide recognition, efflux and/or deactivation.

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Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.

http://www.wikidata.org/entity/Q35682250

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2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Drug interactions with Bacillu ...... inolone action and resistance.

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Drug interactions with Bacillu ...... inolone action and resistance.

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Drug interactions with Bacillu ...... inolone action and resistance.

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Drug interactions with Bacillu ...... inolone action and resistance.

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Drug interactions with Bacillu ...... inolone action and resistance.

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Drug interactions with Bacillu ...... inolone action and resistance.

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Drug interactions with Bacillu ...... inolone action and resistance.

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P2093

Charles L Turnbough

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David E Graves

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Katie J Aldred

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Neil Osheroff

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Pengfei Wang

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Robert J Kerns

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Sylvia A McPherson

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P2860

DNA T OPOISOMERASES : Structure, Function, and Mechanism

DNA gyrase, topoisomerase IV, and the 4-quinolones

Structural basis of gate-DNA breakage and resealing by type II topoisomerases

Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases

A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases

Type IIA topoisomerase inhibition by a new class of antibacterial agents

Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance

A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs

Mode of action of fluoroquinolones.

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370-381

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scholarly article

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10.1021/BI2013905

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1

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51

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22126453

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