Molecular mechanisms of receptor desensitization using the beta-adrenergic receptor-coupled adenylate cyclase system as a model.
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Ethanol blocks adenosine uptake via inhibiting the nucleoside transport system in bronchial epithelial cellsA dynamic interface between ubiquitylation and cAMP signalingSaccharomyces cerevisiae mutants unresponsive to alpha-factor pheromone: alpha-factor binding and extragenic suppression.G beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interactionInsulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1.Long-term, heterologous down-regulation of the epidermal growth factor receptor in PC12 cells by nerve growth factorBeta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptorDesensitization of angiotensin II: effect on [Ca2+]i, inositol triphosphate, and prolactin in pituitary cells.Desensitization of rat renal thick ascending limb cells to vasopressin.Dual effects of serotonin on a voltage-gated conductance in lymphocytesDown-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels.Ligand-induced desensitization of B-cell membrane immunoglobulin-mediated Ca2+ mobilization and protein kinase C translocation.Beta-adrenergic receptors: astrocytic localization in the adult visual cortex and their relation to catecholamine axon terminals as revealed by electron microscopic immunocytochemistry.Internalization of vasopressin analogs in kidney and smooth muscle cells: evidence for receptor-mediated endocytosis in cells with V2 or V1 receptorsGNAS gene variants affect β-blocker-related survival after coronary artery bypass grafting.In vitro desensitization of isolated nephron segments to vasopressin.Myocardial beta-adrenergic receptor function during the development of pacing-induced heart failureMolecular mechanisms in down-regulation of tumor necrosis factor expression.Decreased Gs alpha mRNA levels accompany the fall in Gs and adenylyl cyclase activities in compensated left ventricular hypertrophy. In heart failure, only the impairment in adenylyl cyclase activation progresses.Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats.cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposureStimulation of beta-adrenergic receptors of S49 lymphoma cells redistributes the alpha subunit of the stimulatory G protein between cytosol and membranes.Direct or C5a-induced activation of heterotrimeric Gi2 proteins in human neutrophils is associated with interaction between formyl peptide receptors and the cytoskeleton.Biology of pancreatic cancerDirect relationship between mononuclear leukocyte and lung beta-adrenergic receptors and apparent reciprocal regulation of extravascular, but not intravascular, alpha- and beta-adrenergic receptors by the sympathochromaffin system in humans.Desensitization to parathyroid hormone in renal cells from aged rats is associated with alterations in G-protein activity3-Phosphoglycerate-dependent protein phosphorylationAlpha 2-adrenergic receptor-mediated sensitization of forskolin-stimulated cyclic AMP production.THE ROLE OF β-ADRENERGIC RECEPTORS IN HEART FAILURE: DIFFERENTIAL REGULATION OF CARDIOTOXICITY AND CARDIOPROTECTION.In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptorsPhosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress.Apparent tolerance to the acute effect of nicotine results in part from distribution kinetics.In vivo regulation of beta-adrenergic receptors on mononuclear leukocytes and heart. Assessment of receptor compartmentation after agonist infusion and acute aortic constriction in guinea pigs.Decreased adrenergic neuronal uptake activity in experimental right heart failure. A chamber-specific contributor to beta-adrenoceptor downregulation.Cardiac GPCRs: GPCR signaling in healthy and failing hearts.Adenosine receptors on human airway epithelia and their relationship to chloride secretionBlockade by the local anaesthetic, tetracaine, of desensitization of Ca-induced Ca release after muscarinic stimulation in smooth muscleRegulation of the affinity state of the N-formylated peptide receptor of neutrophils: role of guanine nucleotide-binding proteins and the cytoskeleton.Structural characteristics of gap junctions. I. Channel number in coupled and uncoupled conditions.Detection of an intermediate compartment involved in transport of alpha-factor from the plasma membrane to the vacuole in yeast
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P2860
Molecular mechanisms of receptor desensitization using the beta-adrenergic receptor-coupled adenylate cyclase system as a model.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
Molecular mechanisms of recept ...... ate cyclase system as a model.
@en
Molecular mechanisms of recept ...... ate cyclase system as a model.
@nl
type
label
Molecular mechanisms of recept ...... ate cyclase system as a model.
@en
Molecular mechanisms of recept ...... ate cyclase system as a model.
@nl
prefLabel
Molecular mechanisms of recept ...... ate cyclase system as a model.
@en
Molecular mechanisms of recept ...... ate cyclase system as a model.
@nl
P356
P1433
P1476
Molecular mechanisms of recept ...... ate cyclase system as a model.
@en
P2093
Lefkowitz RJ
P2860
P2888
P304
P356
10.1038/317124A0
P407
P577
1985-09-01T00:00:00Z
P6179
1045130443