G beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interaction
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The R7 RGS protein family: multi-subunit regulators of neuronal G protein signalingD1 dopamine receptor signaling is modulated by the R7 RGS protein EAT-16 and the R7 binding protein RSBP-1 in Caenoerhabditis elegans motor neuronsPalmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.Genome-wide transcriptome profiling of region-specific vulnerability to oxidative stress in the hippocampusRNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling.Regulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics.Helix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex.Monitoring caspase activity in living cells using fluorescent proteins and flow cytometry.Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells.A unique role of RGS9-2 in the striatum as a positive or negative regulator of opiate analgesiaRegulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling.Analyses of the effects of Gq protein on the activated states of the muscarinic M3 receptor and the purinergic P2Y1 receptor.Molecular engineering of DNA: molecular beacons.Cellular and Subcellular Localization of the RGS7/Gβ5/R7BP Complex in the Cerebellar CortexStructure, function, and localization of Gβ5-RGS complexes.Visualization of bHLH transcription factor interactions in living mammalian cell nuclei and developing chicken neural tube by FRET.Chronic cold exposure increases RGS7 expression and decreases alpha(2)-autoreceptor-mediated inhibition of noradrenergic locus coeruleus neurons.The Gbeta5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gbeta(5)-RGS7.Genetic or pharmacological inactivation of the dopamine D1 receptor differentially alters the expression of regulator of G-protein signalling (Rgs) transcripts.
P2860
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P2860
G beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interaction
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@ast
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@en
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@nl
type
label
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@ast
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@en
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@nl
altLabel
Gβ5·RGS7 Inhibits Gαq-mediated Signaling via a Direct Protein-Protein Interaction
@en
prefLabel
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@ast
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@en
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@nl
P2093
P2860
P356
P1476
G beta 5.RGS7 inhibits G alpha ...... ct protein-protein interaction
@en
P2093
Gary B Willars
Qiang Wang
Steven C Tovey
Vladlen Z Slepak
P2860
P304
21307-21313
P356
10.1074/JBC.M212884200
P407
P577
2003-04-01T00:00:00Z