Bilinear Model for the Size-Dependency of the CYP3A4 Inhibitory Activity of Structurally Diverse Compounds.

about

Bilinear Model for the Size-Dependency of the CYP3A4 Inhibitory Activity of Structurally Diverse Compounds.

Item

http://www.wikidata.org/entity/Q39531866

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Bilinear Model for the Size-De ...... tructurally Diverse Compounds.

@en

Bilinear Model for the Size-De ...... tructurally Diverse Compounds.

@nl

type

Item

label

Bilinear Model for the Size-De ...... tructurally Diverse Compounds.

@en

Bilinear Model for the Size-De ...... tructurally Diverse Compounds.

@nl

prefLabel

Bilinear Model for the Size-De ...... tructurally Diverse Compounds.

@en

Bilinear Model for the Size-De ...... tructurally Diverse Compounds.

@nl

P1476

Bilinear Model for the Size-De ...... tructurally Diverse Compounds.

@en

P2093

Fumiyoshi Yamashita

http://www.w3.org/2001/XMLSchema#string

P2860

QSAR modeling of in vitro inhibition of cytochrome P450 3A4.

General linearized biexponential model for QSAR data showing bilinear-type distribution.

Predicting in vivo drug interactions from in vitro drug discovery data.

Quantitative structure-activity relationships (QSARs) within substrates of human cytochromes P450 involved in drug metabolism.

Structural basis for ligand promiscuity in cytochrome P450 3A4.

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios.

Managing the challenge of chemically reactive metabolites in drug development.

Design of drugs involving the concepts and theories of drug metabolism and pharmacokinetics.

CYP3A4 drug interactions: correlation of 10 in vitro probe substrates.

Development of a generalized, quantitative physicochemical model of CYP3A4 inhibition for use in early drug discovery.

P304

8-14

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/MINF.201300132

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Peter Buchwald

P577

2013-12-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

259540430

http://www.w3.org/2001/XMLSchema#string

P698

27485194

http://www.w3.org/2001/XMLSchema#string