Epac1 promotes melanoma metastasis via modification of heparan sulfate.
about
Store-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migrationExchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeuticsA novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasionIsoform-specific antagonists of exchange proteins directly activated by cAMPPharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo.The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention.EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer.Epac1 knockdown inhibits the proliferation of ovarian cancer cells by inactivating AKT/Cyclin D1/CDK4 pathway in vitro and in vivo.Epac1 increases migration of endothelial cells and melanoma cells via FGF2-mediated paracrine signaling.Transient receptor potential cation 3 channel regulates melanoma proliferation and migration.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
P2860
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P2860
Epac1 promotes melanoma metastasis via modification of heparan sulfate.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Epac1 promotes melanoma metastasis via modification of heparan sulfate.
@en
Epac1 promotes melanoma metastasis via modification of heparan sulfate.
@nl
type
label
Epac1 promotes melanoma metastasis via modification of heparan sulfate.
@en
Epac1 promotes melanoma metastasis via modification of heparan sulfate.
@nl
prefLabel
Epac1 promotes melanoma metastasis via modification of heparan sulfate.
@en
Epac1 promotes melanoma metastasis via modification of heparan sulfate.
@nl
P2093
P2860
P1476
Epac1 promotes melanoma metastasis via modification of heparan sulfate
@en
P2093
Erdene Baljinnyam
James S Goydos
Kousaku Iwatsubo
Mariana S De Lorenzo
Mizuka Iwatsubo
Suzie Chen
P2860
P304
P356
10.1111/J.1755-148X.2011.00863.X
P577
2011-05-13T00:00:00Z