c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance.
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Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and TumorogenesisGenomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancersAn inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cellsRestoration of tumor suppressor functions by small-molecule inhibitorsThe Dual Roles of MYC in Genomic Instability and Cancer ChemoresistanceThe 3'-5' DNA exonuclease TREX1 directly interacts with poly(ADP-ribose) polymerase-1 (PARP1) during the DNA damage response.Targeting poly (ADP-ribose) polymerase partially contributes to bufalin-induced cell death in multiple myeloma cells.Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ationIdentification of a novel effector domain of BIN1 for cancer suppression.Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases.Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury.The c-MYC-ABCB5 axis plays a pivotal role in 5-fluorouracil resistance in human colon cancer cells.Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Predicts Poor Survival of Breast Carcinoma Patients.BAR proteins in cancer and blood disordersTargeting c-MYC in Platinum-Resistant Ovarian CancerIndividual and Combined Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Predict Shorter Survival of Soft Tissue Sarcoma Patients.Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxelPoly(ADP-ribose) polymerase 1 regulates nuclear reprogramming and promotes iPSC generation without c-Myc.To die, or not to die: E2F1 never decides by itself during serum starvationAltered glutamine metabolism in platinum resistant ovarian cancer.Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation.The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer.Therapeutic Approaches Targeting MYC-Driven Prostate CancerSulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancerDevelopment of anticancer drugs based on the hallmarks of tumor cells.Amphiphysin 2 (BIN1) in physiology and diseases.Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins.Therapeutic Targeting of Poly(ADP-Ribose) Polymerase-1 (PARP1) in Cancer: Current Developments, Therapeutic Strategies, and Future Opportunities.Addressing intra-tumoral heterogeneity and therapy resistance.Anoikis-resistant subpopulations of human osteosarcoma display significant chemoresistance and are sensitive to targeted epigenetic therapies predicted by expression profilingPET of Poly (ADP-Ribose) Polymerase Activity in Cancer: Preclinical Assessment and First In-Human Studies.MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors.Gemcitabine-based regimen for primary ovarian angiosarcoma with MYC amplification.Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors.Mechanisms of Cisplatin-Induced Apoptosis and of Cisplatin Sensitivity: Potential of BIN1 to Act as a Potent Predictor of Cisplatin Sensitivity in Gastric Cancer Treatment.Amelioration of cisplatin-induced nephrotoxicity in peroxiredoxin I-deficient mice.Let-7d increases ovarian cancer cell sensitivity to a genistein analog by targeting c-Myc.[c-MYC, PARP1 and BIN1 as targets for therapy of cancer cell resistance].Non-Coding RNAs and Resistance to Anticancer Drugs in Gastrointestinal Tumors.Effect of RIF1 on response of non-small-cell lung cancer patients to platinum-based chemotherapy by regulating MYC signaling pathway
P2860
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P2860
c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
c-MYC suppresses BIN1 to release poly
@nl
c-MYC suppresses BIN1 to relea ...... acquire cisplatin resistance.
@en
type
label
c-MYC suppresses BIN1 to release poly
@nl
c-MYC suppresses BIN1 to relea ...... acquire cisplatin resistance.
@en
prefLabel
c-MYC suppresses BIN1 to release poly
@nl
c-MYC suppresses BIN1 to relea ...... acquire cisplatin resistance.
@en
P2093
P1433
P1476
c-MYC suppresses BIN1 to relea ...... acquire cisplatin resistance.
@en
P2093
Chungyoul Choe
Daitoku Sakamuro
Erica K Cassimere
Kazi M Ahmed
Satoshi Tanida
Slovénie Pyndiah
P356
10.1126/SCISIGNAL.2001556
P577
2011-03-29T00:00:00Z