Conjugated linoleic acids mediate insulin release through islet G protein-coupled receptor FFA1/GPR40.
about
Conjugated linoleic acid-induced apoptosis in mouse mammary tumor cells is mediated by both G protein coupled receptor-dependent activation of the AMP-activated protein kinase pathway and by oxidative stress.Cross-sectional study of conjugated linoleic acid in adipose tissue and risk of diabetesOleic acid attenuates trans-10,cis-12 conjugated linoleic acid-mediated inflammatory gene expression in human adipocytes.Conjugated linoleic acid reduces adiposity and increases markers of browning and inflammation in white adipose tissue of miceDiacylglycerol kinase inhibitor R59022 attenuates conjugated linoleic acid-mediated inflammation in human adipocytes.Drugs or diet?--Developing novel therapeutic strategies targeting the free fatty acid family of GPCRsLongitudinal profiling of the tissue-specific expression of genes related with insulin sensitivity in dairy cows during lactation focusing on different fat depots.Approaches for probing allosteric interactions at 7 transmembrane spanning receptors.Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.Detection of free fatty acid receptor 1 expression: the critical role of negative and positive controls.Role of the lower and upper intestine in the production and absorption of gut microbiota-derived PUFA metabolites.Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids.Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance.G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1.Ligands at Free Fatty Acid Receptor 1 (GPR40).Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells.Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseasesLabel-Free Biosensors for Cell Biology
P2860
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P2860
Conjugated linoleic acids mediate insulin release through islet G protein-coupled receptor FFA1/GPR40.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Conjugated linoleic acids medi ...... n-coupled receptor FFA1/GPR40.
@en
Conjugated linoleic acids medi ...... n-coupled receptor FFA1/GPR40.
@nl
type
label
Conjugated linoleic acids medi ...... n-coupled receptor FFA1/GPR40.
@en
Conjugated linoleic acids medi ...... n-coupled receptor FFA1/GPR40.
@nl
prefLabel
Conjugated linoleic acids medi ...... n-coupled receptor FFA1/GPR40.
@en
Conjugated linoleic acids medi ...... n-coupled receptor FFA1/GPR40.
@nl
P2093
P2860
P356
P1476
Conjugated linoleic acids medi ...... in-coupled receptor FFA1/GPR40
@en
P2093
Christel Drewke
Evi Kostenis
Helga Sauerwein
Jesús Gomeza
Johannes Schmidt
Kathrin Liebscher
Manfred Mielenz
Manuel Grundmann
Maria E Due-Hansen
Nicole Merten
P2860
P304
11890-11894
P356
10.1074/JBC.C110.200477
P407
P577
2011-02-21T00:00:00Z