Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

Item

http://www.wikidata.org/entity/Q39617678

Q39617678

about

Spanning the genomics era: the vital role of a single institution biorepository for childhood cancer research over a decade Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility The role of the Hippo pathway in human disease and tumorigenesis KIBRA: In the brain and beyond ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1.A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients.KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis.Serum KIBRA mRNA and Protein Expression and Cognitive Functions in Depression KIBRA promotes prostate cancer cell proliferation and motility.Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2.Regulation of the Hippo pathway and implications for anticancer drug development.WWC3 downregulation correlates with poor prognosis and inhibition of Hippo signaling in human gastric cancer.Hippo pathway deregulation: implications in the pathogenesis of haematological malignancies.Phospho-regulation of KIBRA by CDK1 and CDC14 phosphatase controls cell-cycle progression.Promoter methylation inhibits expression of tumor suppressor KIBRA in human clear cell renal cell carcinoma.High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis.miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis.KIBRA attains oncogenic activity by repressing RASSF1A.KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer.ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA.Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration.Association of peripheral blood leukocyte KIBRA methylation with gastric cancer risk: a case-control study.KIBRAgene methylation is associated with unfavorable biological prognostic parameters in chronic lymphocytic leukemia

P2860

Q26770333-E130DCAD-9BF6-407E-A1E9-F2A0D91DDE86 Q28304661-9FC18C63-F069-4699-9B3C-D816A4EA8338 Q30433413-F558DCE8-EF61-4E75-8473-52AB279C01D1 Q33656456-A0C3F3D9-EB25-4B01-B38D-2B78079C30FA Q34548405-408155AF-D0EA-4F48-BC2C-1CEAE3E68AA3 Q35378440-C48993A3-E77E-4490-BB65-FDD361CA4B11 Q36241388-40CFC1B6-A388-4576-A504-51871F6F2E2A Q36298322-9B7D5F69-1754-45B3-9143-F23690BADAE8 Q36473465-284E6847-F14F-4317-A4BE-13C868AA6DCC Q36935991-3A17D8B0-C946-438A-8CA7-E41E775B47B2 Q37082635-AABE1DBB-477D-4D60-B3B9-71780D5C9137 Q37593084-BE409081-CE64-4B6A-B65C-A76A06F33F0A Q38698941-556E17B9-DA10-458B-98A8-ABA72868F327 Q38995148-21B37361-AA9A-493D-97FE-2E02F3D27F67 Q39316504-C9F62423-436B-411E-9D42-9227CC1F1445 Q42376523-D4C33E3E-0C6E-4F9D-AE98-CCF91B5FAC1B Q43877393-A16890E4-42A7-484A-BCAD-78AAF7C78A47 Q48171440-259A083A-81D5-4875-B15D-11C36AD39882 Q50915279-BE7F7C45-19E1-4856-8774-6C51D6D23AF7 Q52347720-FBD3C3E9-0FC4-415F-8A7C-F010B1B8FD7A Q52663576-04FC24CF-6860-4799-81B9-53F2B0FFBDE4 Q54331848-9B53AB26-7464-4F71-84D4-C8A6E0907292 Q55339998-A64855D7-506C-4D65-A1C4-815CAAC0AA1F Q58041990-1D149F2A-485E-4286-B261-2AEDC23FE579

P2860

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

Item

http://www.wikidata.org/entity/Q39617678

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Frequent epigenetic inactivati ...... ll acute lymphocytic leukemia.

@en

Frequent epigenetic inactivati ...... ll acute lymphocytic leukemia.

@nl

type

Item

label

Frequent epigenetic inactivati ...... ll acute lymphocytic leukemia.

@en

Frequent epigenetic inactivati ...... ll acute lymphocytic leukemia.

@nl

prefLabel

Frequent epigenetic inactivati ...... ll acute lymphocytic leukemia.

@en

Frequent epigenetic inactivati ...... ll acute lymphocytic leukemia.

@nl

P1476

Frequent epigenetic inactivati ...... ell acute lymphocytic leukemia

@en

P2093

Daniel Catchpoole

http://www.w3.org/2001/XMLSchema#string

Dietmar Krex

http://www.w3.org/2001/XMLSchema#string

Eamonn R Maher

http://www.w3.org/2001/XMLSchema#string

Farida Latif

http://www.w3.org/2001/XMLSchema#string

Mike Griffiths

http://www.w3.org/2001/XMLSchema#string

Victoria K Hill

http://www.w3.org/2001/XMLSchema#string

P2860

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis

An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation

Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers

KIBRA is a novel substrate for protein kinase Czeta

Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

P304

326-332

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4161/EPI.6.3.14404

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Thomas L Dunwell

Anna T. Brini

Charles Craddock

P577

2011-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49698026

http://www.w3.org/2001/XMLSchema#string

P698

21173572

http://www.w3.org/2001/XMLSchema#string

P921

leukemia

lymphocyte

P932

3092681

http://www.w3.org/2001/XMLSchema#string

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

about

P2860

P2860

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P921

P932