IL-6 signaling via the STAT3/SOCS3 pathway: functional analysis of the conserved STAT3 N-domain
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Crif1 is a novel transcriptional coactivator of STAT3STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transductionThe small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells.The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation.Innate immune regulation by STAT-mediated transcriptional mechanisms.Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation.Noncanonical STAT3 activation regulates excess TGF-β1 and collagen I expression in muscle of stricturing Crohn's disease.Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen speciesSTAT1 is Constitutively Activated in the T/C28a2 Immortalized Juvenile Human Chondrocyte Line and Stimulated by IL-6 Plus Soluble IL-6RImpact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional ActivitySOCS3 Methylation Predicts a Poor Prognosis in HBV Infection-Related Hepatocellular Carcinoma.STAT5 requires the N-domain to maintain hematopoietic stem cell repopulating function and appropriate lymphoid-myeloid lineage output.G-CSF-activated STAT3 enhances production of the chemokine MIP-2 in bone marrow neutrophils.Identification of novel small molecules that inhibit STAT3-dependent transcription and function.STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domainInhibition of STAT3 expression and signaling in resveratrol-differentiated medulloblastoma cells.Suppressed Th17 levels correlate with elevated PIAS3, SHP2, and SOCS3 expression in CD4 T cells during acute simian immunodeficiency virus infection.The STAT3 NH2-terminal domain stabilizes enhanceosome assembly by interacting with the p300 bromodomain.Interleukin-6 stimulates circulating blood-derived endothelial progenitor cell angiogenesis in vitroIL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting.Interleukin-10 regulates the fetal hyaluronan-rich extracellular matrix via a STAT3-dependent mechanism.Involvement of SOCS3 in regulation of CD11c+ dendritic cell-derived osteoclastogenesis and severe alveolar bone loss.Function of mitochondrial Stat3 in cellular respirationA novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells.Peginesatide and erythropoietin stimulate similar erythropoietin receptor-mediated signal transduction and gene induction events.Hepatitis delta virus induces specific DNA methylation processes in Huh-7 liver cancer cells.STAT3 and Oct-3/4 control histone modification through induction of Eed in embryonic stem cells.Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation.STAT3 signaling pathway is involved in decitabine induced biological phenotype regulation of acute myeloid leukemia cellsA new role for STAT3 as a regulator of chromatin topology.Cellular and Oxidative Mechanisms Associated with Interleukin-6 Signaling in the Vasculature.A mathematical model for IL-6-mediated, stem cell driven tumor growth and targeted treatment.A Reappraisal on the Potential Ability of Human Neutrophils to Express and Produce IL-17 Family Members In Vitro: Failure to Reproducibly Detect It.
P2860
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P2860
IL-6 signaling via the STAT3/SOCS3 pathway: functional analysis of the conserved STAT3 N-domain
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
IL-6 signaling via the STAT3/S ...... f the conserved STAT3 N-domain
@en
IL-6 signaling via the STAT3/S ...... the conserved STAT3 N-domain.
@nl
type
label
IL-6 signaling via the STAT3/S ...... f the conserved STAT3 N-domain
@en
IL-6 signaling via the STAT3/S ...... the conserved STAT3 N-domain.
@nl
prefLabel
IL-6 signaling via the STAT3/S ...... f the conserved STAT3 N-domain
@en
IL-6 signaling via the STAT3/S ...... the conserved STAT3 N-domain.
@nl
P2093
P2860
P1476
IL-6 signaling via the STAT3/S ...... f the conserved STAT3 N-domain
@en
P2093
Donna B Badgwell
Jack J Bevers
Karni Schlessinger
Ling Zhang
Peter J Murray
P2860
P2888
P304
P356
10.1007/S11010-006-9137-3
P577
2006-05-23T00:00:00Z