about
Formation of extrachromosomal circular amplicons with direct or inverted duplications in drug-resistant Leishmania tarentolaeAmplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaksGene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakageSuppression of gene amplification and chromosomal DNA integration by the DNA mismatch repair systemMYC abrogates p53-mediated cell cycle arrest in N-(phosphonacetyl)-L-aspartate-treated cells, permitting CAD gene amplification.Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expressionStructure and evolution of the U2 small nuclear RNA multigene family in primates: gene amplification under natural selection?Deletion of stably integrated DNA is suppressed by cadmium and zinc.From amplification to gene in thyroid cancer: a high-resolution mapped bacterial-artificial-chromosome resource for cancer chromosome aberrations guides gene discovery after comparative genome hybridization.RNA-dependent control of gene amplification.Ectopic mitotic recombination in Drosophila probed with bacterial beta-galactosidase gene-based reporter transgenes.Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase IDNA methylation prevents the amplification of TROP1, a tumor-associated cell surface antigen gene.The role of the replication licensing system in cell proliferation and cancer.Amplification of polyomavirus DNA sequences stably integrated in rat cells.Elements which stimulate gene amplification in mammalian cells: role of recombinogenic sequences/structures and transcriptional activationGene amplification in Rhizobium: identification and in vivo cloning of discrete amplifiable DNA regions (amplicons) from Rhizobium leguminosarum biovar phaseoliExpression cloning of cDNAs that render cancer cells resistant to Pseudomonas and diphtheria toxin and immunotoxins.Induction of circles of heterogeneous sizes in carcinogen-treated cells: two-dimensional gel analysis of circular DNA molecules.Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells.Unstable amplification of two extrachromosomal elements in alpha-difluoromethylornithine-resistant Leishmania donovani.Isolation and structural analysis of a 1.2-megabase N-myc amplicon from a human neuroblastoma.Chromosomal destabilization during gene amplification.Carcinogen-induced DNA amplification in vitro: overreplication of the simian virus 40 origin region in extracts from carcinogen-treated CO60 cellsMethotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation.Evolution and stability of chromosomal DNA coamplified with the CAD geneAmplified DNAs in laboratory stocks of Leishmania tarentolae: extrachromosomal circles structurally and functionally similar to the inverted-H-region amplification of methotrexate-resistant Leishmania major.Is it time for a new paradigm for systemic cancer treatment? Lessons from a century of cancer chemotherapyERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridizationGenetic and physical map of plasmid NR1: comparison with other IncFII antibiotic resistance plasmids.Stable transformation of a mosquito cell line results in extraordinarily high copy numbers of the plasmidRecurrent and nonrandom DNA copy number and chromosome alterations in Myc transgenic mouse model for hepatocellular carcinogenesis: implications for human disease.Double minute chromosomes carrying the human multidrug resistance 1 and 2 genes are generated from the dimerization of submicroscopic circular DNAs in colchicine-selected KB carcinoma cellsFormation of DNA triplexes accounts for arrests of DNA synthesis at d(TC)n and d(GA)n tracts.Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles.An elementary approach to modeling drug resistance in cancer.Early appearance and long-term persistence of the submicroscopic extrachromosomal elements (amplisomes) containing the amplified DHFR genes in human cell lines.Characterization of adenovirus-induced inverted terminal repeat-independent amplification of integrated adeno-associated virus rep-cap sequencesInduction of the bovine papillomavirus origin "onion skin"-type DNA replication at high E1 protein concentrations in vivo.In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes.
P2860
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P2860
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Gene amplification in cultured cells.
@en
Gene amplification in cultured cells.
@nl
type
label
Gene amplification in cultured cells.
@en
Gene amplification in cultured cells.
@nl
prefLabel
Gene amplification in cultured cells.
@en
Gene amplification in cultured cells.
@nl
P1476
Gene amplification in cultured cells.
@en
P2093
Schimke RT
P304
P407
P577
1988-05-01T00:00:00Z