RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA.
about
The killing of African trypanosomes by ethidium bromideKinetoplast DNA network: evolution of an improbable structureDual localization of human DNA topoisomerase IIIalpha to mitochondria and nucleusThe developmental cell biology of Trypanosoma bruceiTbAGO1, an argonaute protein required for RNA interference, is involved in mitosis and chromosome segregation in Trypanosoma bruceiNovel amidines and analogues as promising agents against intracellular parasites: a systematic reviewPIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregationDiverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma bruceiDynamic localization of Trypanosoma brucei mitochondrial DNA polymerase ID.Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library.Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes.Overexpression of a cytochrome b5 reductase-like protein causes kinetoplast DNA loss in Trypanosoma brucei.Identification of a bacterial-like HslVU protease in the mitochondria of Trypanosoma brucei and its role in mitochondrial DNA replication.Gene disruption of the DNA topoisomerase IB small subunit induces a non-viable phenotype in the hemoflagellate Leishmania majorTbPIF5 is a Trypanosoma brucei mitochondrial DNA helicase involved in processing of minicircle Okazaki fragments.A mitochondrial DNA primase is essential for cell growth and kinetoplast DNA replication in Trypanosoma brucei.TbPIF1, a Trypanosoma brucei mitochondrial DNA helicase, is essential for kinetoplast minicircle replication.The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis.TbKAP6, a mitochondrial HMG box-containing protein in Trypanosoma brucei, is the first trypanosomatid kinetoplast-associated protein essential for kinetoplast DNA replication and maintenanceAsymmetrical division of the kinetoplast DNA network of the trypanosome.Mitochondrial development during life cycle differentiation of African trypanosomes: evidence for a kinetoplast-dependent differentiation control point.Cell cycle-dependent localization and properties of a second mitochondrial DNA ligase in Crithidia fasciculataA new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology.Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1A passion for parasites.A type II ribonuclease H from Leishmania mitochondria: an enzyme essential for the growth of the parasite.Three mitochondrial DNA polymerases are essential for kinetoplast DNA replication and survival of bloodstream form Trypanosoma brucei.Cloning, functional analysis and post-transcriptional regulation of a type II DNA topoisomerase from Leishmania infantum. A new potential target for anti-parasite drugs.Orientation of DNA Minicircles Balances Density and Topological Complexity in Kinetoplast DNA.25 years of African trypanosome research: From description to molecular dissection and new drug discoveryA plethora of targets, a paucity of drugs: progress towards the development of novel chemotherapies for human African trypanosomiasis.RNA-mediated gene silencing: mechanisms and its therapeutic applications.Novel antitrypanosomal agents.Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes.Structure of discontinuities in kinetoplast DNA-associated minicircles during S phase in Crithidia fasciculataTopoisomerases of kinetoplastid parasites: why so fascinating?Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiationMitochondrial DNA ligase in Crithidia fasciculata.Trypanosomes have six mitochondrial DNA helicases with one controlling kinetoplast maxicircle replication.
P2860
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P2860
RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
RNA interference of a trypanos ...... ive loss of mitochondrial DNA.
@en
RNA interference of a trypanos ...... ive loss of mitochondrial DNA.
@nl
type
label
RNA interference of a trypanos ...... ive loss of mitochondrial DNA.
@en
RNA interference of a trypanos ...... ive loss of mitochondrial DNA.
@nl
prefLabel
RNA interference of a trypanos ...... ive loss of mitochondrial DNA.
@en
RNA interference of a trypanos ...... ive loss of mitochondrial DNA.
@nl
P2860
P356
P1433
P1476
RNA interference of a trypanos ...... ive loss of mitochondrial DNA.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/20.17.4674
P407
P577
2001-09-01T00:00:00Z