Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.
about
A mechanosensitive transcriptional mechanism that controls angiogenesisRUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory elementA Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesisThe "Ets" factor: vessel formation in zebrafish--the missing link?Specification and function of hemogenic endothelium during embryogenesisTranscriptional network control of normal and leukaemic haematopoiesisMultiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific mannerErythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expressionDiscovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancyGata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic developmentMolecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesisConBind: motif-aware cross-species alignment for the identification of functional transcription factor binding sitesA novel mode of enhancer evolution: the Tal1 stem cell enhancer recruited a MIR element to specifically boost its activityIdentification of biologically relevant enhancers in human erythroid cells.From mice to humans: identification of commonly deregulated genes in mammary cancer via comparative SAGE studies.Real-time PCR mapping of DNaseI-hypersensitive sites using a novel ligation-mediated amplification technique.Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL1) locus.Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate.Potential autoregulation of transcription factor PU.1 by an upstream regulatory elementDirecting oncogenic fusion genes into stem cells via an SCL enhancer.Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineagesHierarchical differentiation of myeloid progenitors is encoded in the transcription factor networkMapping and functional characterisation of a CTCF-dependent insulator element at the 3' border of the murine Scl transcriptional domain.3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation.Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cellsTranscriptional control of erythropoiesis: emerging mechanisms and principles.Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factorsTranscriptional control of endothelial cell development.Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity.Integration of Elf-4 into stem/progenitor and erythroid regulatory networks through locus-wide chromatin studies coupled with in vivo functional validationTranscriptional regulation of haematopoiesis.Effect of transcription-factor concentrations on leukemic stem cells.ETS transcription factors: possible targets for cancer therapy.GATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia.3off2: A network reconstruction algorithm based on 2-point and 3-point information statistics.Deletion of the Scl +19 enhancer increases the blood stem cell compartment without affecting the formation of mature blood lineages.Shared transcription factors contribute to distinct cell fatesA microfluidic device for epigenomic profiling using 100 cells.
P2860
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P2860
Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Establishing the transcription ...... ntaining Ets and GATA factors.
@en
Establishing the transcription ...... ntaining Ets and GATA factors.
@nl
type
label
Establishing the transcription ...... ntaining Ets and GATA factors.
@en
Establishing the transcription ...... ntaining Ets and GATA factors.
@nl
prefLabel
Establishing the transcription ...... ntaining Ets and GATA factors.
@en
Establishing the transcription ...... ntaining Ets and GATA factors.
@nl
P2093
P2860
P50
P356
P1433
P1476
Establishing the transcription ...... ontaining Ets and GATA factors
@en
P2093
Aristotelis Nastos
Maria-Jose Sanchez
Maureen Stanley
Roger Patient
Sandie Piltz
Sarah Kinston
P2860
P304
P356
10.1093/EMBOJ/CDF286
P407
P577
2002-06-01T00:00:00Z