Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane.
about
Retinal iron homeostasis in health and diseaseTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesDifferential gene expression in anatomical compartments of the human eye.Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related DiseasesIron homeostasis and toxicity in retinal degenerationDisruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degenerationIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesEnvironmental cadmium and lead exposures and age-related macular degeneration in U.S. adults: the National Health and Nutrition Examination Survey 2005 to 2008Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degenerationAssociation of Serum Ferritin and Kidney Function with Age-Related Macular Degeneration in the General PopulationDrusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degenerationBrain and retinal ferroportin 1 dysregulation in polycythaemia miceThe complexities underlying age-related macular degeneration: could amyloid beta play an important role?Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).Aceruloplasminemia: retinal histopathologic manifestations and iron-mediated melanosome degradationThe oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice.Iron, the retina and the lens: a focused review.Topical nutraceutical Optixcare EH ameliorates experimental ocular oxidative stress in rats.Long-chain and very long-chain polyunsaturated fatty acids in ocular aging and age-related macular degenerationThe cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.The oral iron chelator deferiprone protects against iron overload-induced retinal degenerationLevels of aqueous humor trace elements in patients with non-exsudative age-related macular degeneration: a case-control studyIron upregulates melanogenesis in cultured retinal pigment epithelial cellsCeruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMDExpression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epitheliumDegeneration modulates retinal response to transient exogenous oxidative injury.Variability of the transferrin receptor 2 gene in AMD.Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-β Signaling in the Retinal Pigment Epithelium.Regulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding siteRetinal phagocytes in age-related macular degenerationIron Toxicity in the Retina Requires Alu RNA and the NLRP3 InflammasomeGenetic polymorphism of the iron-regulatory protein-1 and -2 genes in age-related macular degeneration.Age-dependent and gender-specific changes in mouse tissue iron by strain.Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retinaAn association between environmental factors and the IVS4+44C>A polymorphism of the DMT1 gene in age-related macular degenerationHow does the macula protect itself from oxidative stress?Concentration dependence of vitamin C in combinations with vitamin E and zeaxanthin on light-induced toxicity to retinal pigment epithelial cells.Mice with hepcidin-resistant ferroportin accumulate iron in the retina.Altered expression of the iron transporter Nramp1 (Slc11a1) during fetal development of the retinal pigment epithelium in microphthalmia-associated transcription factor Mitf(mi) and Mitf(vitiligo) mouse mutants.The protective role of transferrin in Müller glial cells after iron-induced toxicity
P2860
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P2860
Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Maculas affected by age-relate ...... ithelium and Bruch's membrane.
@en
Maculas affected by age-relate ...... ithelium and Bruch's membrane.
@nl
type
label
Maculas affected by age-relate ...... ithelium and Bruch's membrane.
@en
Maculas affected by age-relate ...... ithelium and Bruch's membrane.
@nl
prefLabel
Maculas affected by age-relate ...... ithelium and Bruch's membrane.
@en
Maculas affected by age-relate ...... ithelium and Bruch's membrane.
@nl
P1433
P1476
Maculas affected by age-relate ...... pithelium and Bruch's membrane
@en
P2093
Ann H Milam
Joshua L Dunaief
P304
P356
10.1001/ARCHOPHT.121.8.1099
P407
P50
P577
2003-08-01T00:00:00Z