DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. - Wikidata - awgldk - TriplyDB

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

http://www.wikidata.org/entity/Q39657420

about

The clearance of dying cells: table for two Rho GAPs and GEFs: controling switches in endothelial cell adhesion Small G proteins in the cardiovascular system: physiological and pathological aspects PTP1B inhibitor promotes endothelial cell motility by activating the DOCK180/Rac1 pathway.Apoptotic cell recognition receptors and scavenger receptors.ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.Essential role of Elmo1 in Dock2-dependent lymphocyte migration The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.Fine-Tuning of the Actin Cytoskeleton and Cell Adhesion During Drosophila Development by the Unconventional Guanine Nucleotide Exchange Factors Myoblast City and Sponge.Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis.The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets.Insights into the biological functions of Dock family guanine nucleotide exchange factors.I'm coming to GEF you: Regulation of RhoGEFs during cell migration.Pro-survival effect of Dock180 overexpression on rat-derived H9C2 cardiomyocytes Ras GTPases' interaction with effector domains: Breaking the families' barrier.Opening up on ELMO regulation: New insights into the control of Rac signaling by the DOCK180/ELMO complex.The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development.Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation.Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.Increased susceptibility to severe chronic liver damage in CXCR4 conditional knock-out mice.

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P2860

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

http://www.wikidata.org/entity/Q39657420

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

DOCK180 is a Rac activator tha ...... by acting downstream of CXCR4.

@en

DOCK180 is a Rac activator tha ...... by acting downstream of CXCR4.

@nl

type

label

DOCK180 is a Rac activator tha ...... by acting downstream of CXCR4.

@en

DOCK180 is a Rac activator tha ...... by acting downstream of CXCR4.

@nl

prefLabel

DOCK180 is a Rac activator tha ...... by acting downstream of CXCR4.

@en

DOCK180 is a Rac activator tha ...... by acting downstream of CXCR4.

@nl

P1433

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P356

CIRCRESAHA.110.223388

P1433

Circulation Research

P1476

DOCK180 is a Rac activator tha ...... by acting downstream of CXCR4.

@en

P2093

Chikara Meno

http://www.w3.org/2001/XMLSchema#string

Fumiyuki Sanematsu

http://www.w3.org/2001/XMLSchema#string

Guo Ding

http://www.w3.org/2001/XMLSchema#string

Jean-François Côté

http://www.w3.org/2001/XMLSchema#string

Keiko Kitajima

http://www.w3.org/2001/XMLSchema#string

Mamiko Noda

http://www.w3.org/2001/XMLSchema#string

Masanori Hirashima

http://www.w3.org/2001/XMLSchema#string

Mélanie Laurin

http://www.w3.org/2001/XMLSchema#string

Ryosuke Takii

http://www.w3.org/2001/XMLSchema#string

Sadahiko Masuko

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling.

Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

The role of CXCL12 in the organ-specific process of artery formation

P304

1102-1105

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P31

scholarly article

P356

10.1161/CIRCRESAHA.110.223388

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P433

9

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P478

107

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P50

Akihiko Nishikimi

Yoshinori Fukui

P577

2010-09-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20829512

http://www.w3.org/2001/XMLSchema#string

P921

Aparato circulatorio

P932

4640903

http://www.w3.org/2001/XMLSchema#string