Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene. - Wikidata - awgldk - TriplyDB

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.

http://www.wikidata.org/entity/Q39659874

about

The transcription factor p53: not a repressor, solely an activator Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids Characterization of the p53 response to oncogene-induced senescence.Localization of hepatocyte nuclear factor-4α in the nucleolus and nucleus is regulated by its C-terminus Involvement of NF-kappaB activation in the apoptosis induced by extracellular adenosine in human hepatocellular carcinoma HepG2 cells.Nuclear receptor HNF4α binding sequences are widespread in Alu repeats HNF4α--role in drug metabolism and potential drug target?p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation Role of hepatocyte nuclear factor 4α in controlling copper-responsive transcription.p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes.The anti-hypercholesterolemic effect of low p53 expression protects vascular endothelial function in mice HBx down-regulated Gld2 plays a critical role in HBV-related dysregulation of miR-122 Mdm2 is a novel activator of ApoCIII promoter which is antagonized by p53 and SHP inhibition Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Intelectin 1 suppresses tumor progression and is associated with improved survival in gastric cancer.Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter.Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4α and contributes to cell cycle control in hepatoma cells.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.Wild-type p53 and p73 negatively regulate expression of proliferation related genes.Regulation of hepatocyte identity and quiescence.Orphan nuclear receptor PNR/NR2E3 stimulates p53 functions by enhancing p53 acetylation The yin and yang of proliferation and differentiation: cyclin D1 inhibits differentiation factors ChREBP and HNF4α.

P2860

Q24273295-E51BA944-F7C5-408B-AA8A-A16A9B4C2961 Q28080239-BCCF8098-A73D-4CAC-A794-F6FB301DB682 Q33370291-2A567DDB-EFC7-4DA3-9BE4-BF0070745080 Q33603307-6325ECC1-23F8-49A7-B17A-B5420195761F Q33638303-BFCD351C-2F50-451F-8DF1-78518ED20633 Q34075027-5EE1781F-5947-4CED-A75F-A028B6E0ABAD Q34311568-11377663-B2B8-4E91-9E11-530A9B492ED1 Q34388165-80BC9393-927E-4B35-822F-3F049C695060 Q34459126-4EB9C490-1B44-4A1E-9863-200BACB9DE63 Q34708518-DA5E3A29-0474-496B-9323-11C19BEC7024 Q35125397-22B71079-4B2B-4B71-A4E5-87E5AED5C590 Q35131026-90838950-D13B-479B-92C8-69FCC79F0B15 Q35675337-2481413F-669A-4638-AA3E-B29AB4529500 Q36070016-CCECBAC8-C4B9-4267-A39C-39C2782E7E0C Q36140759-6790BE36-CB39-4E3B-BA29-15BD0DA2BAA5 Q36372654-9E9204B9-8A8E-48B4-B3AC-362AC4D34BEB Q36962536-9907E38C-70F2-4F7E-859A-E9192E88F50C Q37857673-F6405266-AA6B-4AC4-8D71-C980E220EA8C Q38296687-0A9FFCA4-8801-4500-B6BA-8FC2ABED4F8A Q38531851-2C11107F-0720-4DF2-B6C8-AC0240DCCFB6 Q39453113-C99DC846-13F5-4B76-87AF-7971BD2E56D1 Q42446120-83E6ACAC-0E9D-4762-9AD5-15035E3D13EA

P2860

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.

http://www.wikidata.org/entity/Q39659874

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

Tumour suppressor p53 down-reg ...... actor 4alpha (HNF4alpha) gene.

@en

Tumour suppressor p53 down-reg ...... patocyte nuclear factor 4alpha

@nl

type

label

Tumour suppressor p53 down-reg ...... actor 4alpha (HNF4alpha) gene.

@en

Tumour suppressor p53 down-reg ...... patocyte nuclear factor 4alpha

@nl

prefLabel

Tumour suppressor p53 down-reg ...... actor 4alpha (HNF4alpha) gene.

@en

Tumour suppressor p53 down-reg ...... patocyte nuclear factor 4alpha

@nl

P1433

Q39659874-1B9F7D90-88D4-44A1-89B3-9A125F1EC07B

P1476

Q39659874-53084380-0D78-4ECC-A320-B11838EBA28A

P2093

Q39659874-0727D09F-0B04-425E-9E7C-8F25B14AFF8D

Q39659874-2E110E43-8E68-43D4-9EE5-9CA0F07847AD

Q39659874-2EE6510E-9280-42F5-8746-9383FD521E74

Q39659874-464898C5-3B57-4A12-9305-C38249672721

Q39659874-A756417C-42F8-4D6C-B5A4-D2CB9F2B0CD2

Q39659874-BBA634F5-376A-4748-8FA8-83B29FD362FD

Q39659874-C039C072-AFF7-4638-A1F8-BD1D5FBF6137

Q39659874-CE68AECC-B22B-454E-8034-99554E5DA1CB

P2860

Q39659874-095EF724-E73F-4694-B0C9-3314A96380DA

Q39659874-1B636743-B745-4D44-B5A7-279058D52350

Q39659874-1E038706-1645-4036-90AC-58B728144EA0

Q39659874-1E566B84-1EB9-4751-8DA6-20F1EDCB175A

Q39659874-2984F7E8-4468-41F8-B9D8-D0DBBB2027AA

Q39659874-2B0C10BB-7A57-40BC-B991-3FFEA8BE9907

Q39659874-2F45D226-E747-47F7-BBBE-B5D5145A22E9

Q39659874-36A3DD93-778A-45C6-B0D1-56E69E50DB84

Q39659874-3987B369-5382-485C-90E4-165F11ACFDFC

Q39659874-3D50C0BC-D5F0-42C8-8ED2-B8FCF9F4FF4F

P304

Q39659874-8864C7C0-40EC-4B91-9C00-2D745D9F2F81

P31

Q39659874-2D8C81C6-6D44-4AC1-B543-2CAC23D32D8B

P356

Q39659874-BB01F624-8BDF-4B2F-9838-331AFEDB947B

P407

Q39659874-23DEBE47-EDB4-45B3-9A70-BCB4B116E911

P433

Q39659874-5948EDCF-E41C-4265-85EB-5EF562EC684E

P478

Q39659874-AC414245-FEE6-40BE-9B1F-3A162FD17B38

P577

Q39659874-044EFA3C-1A26-466E-B161-1F6D70944884

P5875

Q39659874-F8A563F9-ADD6-445E-818A-3AAAE7EA7194

P698

Q39659874-21AF95D9-F642-4922-89DB-940C38754D13

P932

Q39659874-356B575A-5A5E-41BA-9850-134AD5846E56

P356

P1433

Biochemical Journal

P1476

Tumour suppressor p53 down-reg ...... actor 4alpha (HNF4alpha) gene.

@en

P2093

Frances M Sladek

http://www.w3.org/2001/XMLSchema#string

Gang Wei

http://www.w3.org/2001/XMLSchema#string

Laurie B Owen

http://www.w3.org/2001/XMLSchema#string

Mary L Durbin

http://www.w3.org/2001/XMLSchema#string

Takuya Fukazawa

http://www.w3.org/2001/XMLSchema#string

Wendy W Hwang-Verslues

http://www.w3.org/2001/XMLSchema#string

Xuan Liu

http://www.w3.org/2001/XMLSchema#string

Yutaka Maeda

http://www.w3.org/2001/XMLSchema#string

P2860

Wild-type p53 binds to the TATA-binding protein and represses transcription

Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors

Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences

Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205

Mechanisms of hepatotoxicity

Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homeodomain, and define the new ONECUT class of homeodomain proteins

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

p53: puzzle and paradigm

Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver.

P304

303-313

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1042/BJ20060614

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

400

http://www.w3.org/2001/XMLSchema#string

P577

2006-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6890703

http://www.w3.org/2001/XMLSchema#string

P698

16895524

http://www.w3.org/2001/XMLSchema#string

P932

1652821

http://www.w3.org/2001/XMLSchema#string