Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
about
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAsOverexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs.Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistanceChimeric RNase H-competent oligonucleotides directed to the HIV-1 Rev response elementSmall interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral productionMolecular strategies to inhibit HIV-1 replicationBiochemical prevention and treatment of viral infections - a new paradigm in medicine for infectious diseasesHIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genomeHIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vectorLentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophagesModulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infectionHIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors.Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAsOptimization of linear double-stranded RNA for the production of multiple siRNAs targeting hepatitis C virusEngineering T Cells to Functionally Cure HIV-1 InfectionEvasion of innate and adaptive immunity by flavivirusesRNA interference and potential therapeutic applications of short interfering RNAsA Multiple siRNA-Based Anti-HIV/SHIV Microbicide Shows Protection in Both In Vitro and In Vivo Models"UnPAKing" human immunodeficiency virus (HIV) replication: using small interfering RNA screening to identify novel cofactors and elucidate the role of group I PAKs in HIV infectionRNA nanotechnology: engineering, assembly and applications in detection, gene delivery and therapyHepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA.Drosha as an interferon-independent antiviral factor.Selection of potent non-toxic inhibitory sequences from a randomized HIV-1 specific lentiviral short hairpin RNA library.Inhibition of coxsackievirus B3 replication by small interfering RNAs requires perfect sequence match in the central region of the viral positive strand.Characterization and frequency of a newly identified HIV-1 BF1 intersubtype circulating recombinant form in São Paulo, Brazil.The effects of stem length and core placement on shRNA activityInhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cellsIn silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy.Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.Unlocking the potential of the human genome with RNA interference.siRNA therapeutics: big potential from small RNAs.Antiviral effects of human immunodeficiency virus type 1-specific small interfering RNAs against targets conserved in select neurotropic viral strains.RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo.Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site.Lentiviral-mediated delivery of siRNAs for antiviral therapy.The interplay between virus infection and the cellular RNA interference machinery.HIV-1 RT-dependent DNAzyme expression inhibits HIV-1 replication without the emergence of escape viruses.Multiple shRNA combinations for near-complete coverage of all HIV-1 strains
P2860
Q24302072-0DC0244F-251F-42D1-B121-F0019ABAA852Q24324793-2FDAD990-1031-4E7D-BAE2-6EDDA1D04589Q24564647-AEF3AD6B-1B3F-41E0-BB0F-3C90C933FB22Q24682407-8C81E545-E014-48C3-8DDB-DF453A72EA1BQ24682936-09D567F5-099F-4874-86E9-07A372F06475Q24799813-AE8DB23F-0A7B-40C1-BCE4-E2757BD31547Q24801934-6D2FC812-228C-4223-B56E-0F3837192FA1Q24802185-922B3DCC-F867-4052-B603-7DE09D326D4CQ24806310-146D6668-2307-4A2C-B2F1-B84C6690D501Q24806329-953C9507-EFD8-43BF-ADFE-92B78B6197B3Q24808657-B9B0C37C-03E6-47EA-8C3E-96A659BB7A77Q24811688-9DAC042E-F7B6-4C88-B039-99E79A80AA60Q24816355-B744BE7E-562D-4943-8902-A7605E32E4E9Q27473092-42D3DA34-F0B5-4D7E-B4E5-8DBB1772C758Q27488340-FF2346F2-DBEB-4A77-AA4B-064426B47C9FQ28086801-1C0FC7CF-B034-4DAF-A604-433A44ED73B9Q28204656-1F982D73-6AEC-408D-8699-379D08D9E9DCQ28250480-2DD9F69C-F348-4EDA-BC82-696907C8A08FQ30379545-BE21B379-423F-467C-BCAF-C045A9131DD3Q33229419-B2BF4662-A5FB-449C-AC82-B2238375E9AFQ33232299-756431C5-08DE-4C4B-A82B-0D905E3D97EBQ33508709-85BA2294-95AD-457F-A3F3-61220FD725F1Q33627169-F60723A4-76AA-4161-B17D-88089DA7EEA4Q33719287-6B898B51-369E-4B0A-9E02-740FB1DD9C1DQ33781261-ABABA2A2-845D-43F3-8154-60340CE39625Q33809376-94C3A24E-0A1C-40CC-A378-CB05D816E758Q33984111-A869FC7D-57D6-4DF3-8D67-49379AB33C57Q34169244-8EDC9761-FB7A-4786-8237-B5BF55161DF0Q34178401-833F7F78-F208-4A5D-8C47-0EDC67B963C9Q34221633-8F196D98-F4AF-46FF-B272-0F34FC19FA35Q34291247-CC750E2D-59FE-4066-B6A5-5BE963FF0D4DQ34348958-DA9C8048-0B85-4711-999D-0AE4510CDB4EQ34360881-0A59C290-E46A-4C2B-99DF-FFB77DC9688AQ34371320-3BF358AA-27F3-4257-8383-E9CB57BFFA9EQ34379366-2D7AAB28-38BB-4064-8796-A2608A02F13CQ34434986-063B6C6E-C8F8-4E6A-A25B-ABD66A2F1028Q34482299-B08D1C7A-E4E5-4804-A865-CA34AF7E042BQ34505284-52EF89B6-166F-497A-8DC1-30CAA4038D8FQ34513742-EF0315A1-119D-45BA-A92B-A689C4A3D904Q34552467-798C17FE-7A1B-43B9-8BE3-D2F34C5584FC
P2860
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Potent and specific inhibition ...... eplication by RNA interference
@en
Potent and specific inhibition ...... plication by RNA interference.
@nl
type
label
Potent and specific inhibition ...... eplication by RNA interference
@en
Potent and specific inhibition ...... plication by RNA interference.
@nl
prefLabel
Potent and specific inhibition ...... eplication by RNA interference
@en
Potent and specific inhibition ...... plication by RNA interference.
@nl
P2860
P1433
P1476
Potent and specific inhibition ...... eplication by RNA interference
@en
P2093
Bryan R Cullen
Glen A Coburn
P2860
P304
P356
10.1128/JVI.76.18.9225-9231.2002
P407
P577
2002-09-01T00:00:00Z