Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation. - Wikidata - awgldk - TriplyDB

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.

http://www.wikidata.org/entity/Q39697365

about

Repurposing metformin: an old drug with new tricks in its binding pockets Molecular mechanism of action of metformin: old or new insights?Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases AMP-activated protein kinase, stress responses and cardiovascular diseases The AMPK signalling pathway coordinates cell growth, autophagy and metabolism The ancient drug salicylate directly activates AMP-activated protein kinase AMPK activators: mechanisms of action and physiological activities Resveratrol Inhibition of Cellular Respiration: New Paradigm for an Old Mechanism Regulation of AMP-activated protein kinase by natural and synthetic activators Current understanding of metformin effect on the control of hyperglycemia in diabetes Natural Products as Tools for Defining How Cellular Metabolism Influences Cellular Immune and Inflammatory Function during Chronic Infection Neuropharmacological Actions of Metformin in Stroke Resveratrol: A Focus on Several Neurodegenerative Diseases Targeting LKB1 in cancer - exposing and exploiting vulnerabilities Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells Sirtuins as regulators of metabolism and healthspan AMP-activated protein kinase: a target for drugs both ancient and modern Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?AMPK: a target for drugs and natural products with effects on both diabetes and cancer Cellular and molecular mechanisms of metformin: an overview Lysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulation Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans Adenosine monophosphate-activated protein kinase-based classification of diabetes pharmacotherapy The emerging role of AMPK in the regulation of breathing and oxygen supply The hallmarks of aging A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol Lymphocytes accelerate epithelial tight junction assembly: role of AMP-activated protein kinase (AMPK)COH-SR4 reduces body weight, improves glycemic control and prevents hepatic steatosis in high fat diet-induced obese mice Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells Glutathione S-transferases interact with AMP-activated protein kinase: evidence for S-glutathionylation and activation in vitro AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice Activation of AMPK by berberine promotes adiponectin multimerization in 3T3-L1 adipocytes Activation of β-catenin by oncogenic PIK3CA and EGFR promotes resistance to glucose deprivation by inducing a strong antioxidant response AMPK: a nutrient and energy sensor that maintains energy homeostasis Treatment of nonalcoholic fatty liver disease: role of AMPK.AMPK-independent inhibition of human macrophage ER stress response by AICAR.Adenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.

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Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.

http://www.wikidata.org/entity/Q39697365

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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2010年學術文章

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2010年學術文章

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name

Use of cells expressing gamma ...... mechanisms of AMPK activation.

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Use of cells expressing gamma ...... mechanisms of AMPK activation.

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type

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Use of cells expressing gamma ...... mechanisms of AMPK activation.

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Use of cells expressing gamma ...... mechanisms of AMPK activation.

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Use of cells expressing gamma ...... mechanisms of AMPK activation.

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Use of cells expressing gamma ...... mechanisms of AMPK activation.

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J.CMET.2010.04.001

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Cell Metabolism

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Use of cells expressing gamma ...... mechanisms of AMPK activation.

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P2093

A Mark Evans

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Ashleigh Evans

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Cyrille Chevtzoff

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D Grahame Hardie

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Fiona A Ross

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Kevin A Green

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Laura J Brown

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Mhairi C Towler

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Oluseye A Ogunbayo

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Sarah Fogarty

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P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

Role of AMP-activated protein kinase in mechanism of metformin action

Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy

Structural basis for AMP binding to mammalian AMP-activated protein kinase

Fatal congenital heart glycogenosis caused by a recurrent activating R531Q mutation in the gamma 2-subunit of AMP-activated protein kinase (PRKAG2), not by phosphorylase kinase deficiency.

Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle

NAADP mobilizes calcium from acidic organelles through two-pore channels

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

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10.1016/J.CMET.2010.04.001

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6

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