Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation - Wikidata - awgldk - TriplyDB

Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation

Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation

http://www.wikidata.org/entity/Q39698787

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Inhibition of macroautophagy triggers apoptosis Upstream regulatory role for XIAP in receptor-mediated apoptosis Nitric oxide-mediated sensitization of resistant tumor cells to apoptosis by chemo-immunotherapeutics Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways The transmembrane domains of TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 co-regulate apoptotic signaling capacity.Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway.Regulation of apoptosis proteins in cancer cells by ubiquitin.TRAIL and its receptors as targets for cancer therapy.The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell carcinoma of the skin Iso-suillin from Suillus flavus Induces Apoptosis in Human Small Cell Lung Cancer H446 Cell Line.TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer.Induction of apoptosis in experimental human B cell lymphomas by conditional TRAIL-expressing T cells.Proteasome inhibitors: antitumor effects and beyond.Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody Death receptors as targets for anti-cancer therapy.DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.Camptothecin fails to induce apoptosis in tumor necrosis factor-alpha-treated HaCaT cells.Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link.Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95- and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex Distinct TRAIL resistance mechanisms can be overcome by proteasome inhibition but not generally by synergizing agents.Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells.Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kappaB but is related to downregulation of initiator caspases and DR4.Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway.Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors.cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes.Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.Recombinant YopJ induces apoptosis in murine peritoneal macrophages in vitro: involvement of mitochondrial death pathway.The contact allergen nickel sensitizes primary human endothelial cells and keratinocytes to TRAIL-mediated apoptosis.Death receptor-induced signaling pathways are differentially regulated by gamma interferon upstream of caspase 8 processing.Cellular inhibitor of apoptosis-2 is a critical regulator of apoptosis in airway epithelial cells treated with asthma-related inflammatory cytokines.TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis.FLIP ing the coin? Death receptor-mediated signals during skin tumorigenesis.Proteasome inhibitor MG132 sensitizes HPV-positive human cervical cancer cells to rhTRAIL-induced apoptosis.

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Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation

http://www.wikidata.org/entity/Q39698787

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Proteasome inhibition results ...... of effector caspase maturation

@en

Proteasome inhibition results ...... f effector caspase maturation.

@nl

type

label

Proteasome inhibition results ...... of effector caspase maturation

@en

Proteasome inhibition results ...... f effector caspase maturation.

@nl

prefLabel

Proteasome inhibition results ...... of effector caspase maturation

@en

Proteasome inhibition results ...... f effector caspase maturation.

@nl

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MCB.23.3.777-790.2003

P1433

Molecular and Cellular Biology

P1476

Proteasome inhibition results ...... of effector caspase maturation

@en

P2093

Bernd Baumann

http://www.w3.org/2001/XMLSchema#string

Edgar Serfling

http://www.w3.org/2001/XMLSchema#string

Henning Walczak

http://www.w3.org/2001/XMLSchema#string

Manfred Neumann

http://www.w3.org/2001/XMLSchema#string

Martin Leverkus

http://www.w3.org/2001/XMLSchema#string

Martin R Sprick

http://www.w3.org/2001/XMLSchema#string

Matthias Goebeler

http://www.w3.org/2001/XMLSchema#string

Thilo Mengling

http://www.w3.org/2001/XMLSchema#string

Tina Wachter

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P2860

Caspase-10 is an initiator caspase in death receptor signaling

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

Identification and characterization of a new member of the TNF family that induces apoptosis

X-linked IAP is a direct inhibitor of cell-death proteases

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

P304

777-790

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scholarly article

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10.1128/MCB.23.3.777-790.2003

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3

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23

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Eva-Bettina Bröcker

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2003-02-01T00:00:00Z

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P698

12529384

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140698

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