Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation
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Inhibition of macroautophagy triggers apoptosisUpstream regulatory role for XIAP in receptor-mediated apoptosisNitric oxide-mediated sensitization of resistant tumor cells to apoptosis by chemo-immunotherapeuticsTrailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer CellsCellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitmentBortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathwaysThe transmembrane domains of TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 co-regulate apoptotic signaling capacity.Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway.Regulation of apoptosis proteins in cancer cells by ubiquitin.TRAIL and its receptors as targets for cancer therapy.The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell carcinoma of the skinIso-suillin from Suillus flavus Induces Apoptosis in Human Small Cell Lung Cancer H446 Cell Line.TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer.Induction of apoptosis in experimental human B cell lymphomas by conditional TRAIL-expressing T cells.Proteasome inhibitors: antitumor effects and beyond.Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibodyDeath receptors as targets for anti-cancer therapy.DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.Camptothecin fails to induce apoptosis in tumor necrosis factor-alpha-treated HaCaT cells.Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link.Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95- and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complexDistinct TRAIL resistance mechanisms can be overcome by proteasome inhibition but not generally by synergizing agents.Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells.Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kappaB but is related to downregulation of initiator caspases and DR4.Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway.Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors.cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes.Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.Recombinant YopJ induces apoptosis in murine peritoneal macrophages in vitro: involvement of mitochondrial death pathway.The contact allergen nickel sensitizes primary human endothelial cells and keratinocytes to TRAIL-mediated apoptosis.Death receptor-induced signaling pathways are differentially regulated by gamma interferon upstream of caspase 8 processing.Cellular inhibitor of apoptosis-2 is a critical regulator of apoptosis in airway epithelial cells treated with asthma-related inflammatory cytokines.TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis.FLIP ing the coin? Death receptor-mediated signals during skin tumorigenesis.Proteasome inhibitor MG132 sensitizes HPV-positive human cervical cancer cells to rhTRAIL-induced apoptosis.
P2860
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P2860
Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Proteasome inhibition results ...... of effector caspase maturation
@en
Proteasome inhibition results ...... f effector caspase maturation.
@nl
type
label
Proteasome inhibition results ...... of effector caspase maturation
@en
Proteasome inhibition results ...... f effector caspase maturation.
@nl
prefLabel
Proteasome inhibition results ...... of effector caspase maturation
@en
Proteasome inhibition results ...... f effector caspase maturation.
@nl
P2093
P2860
P1476
Proteasome inhibition results ...... of effector caspase maturation
@en
P2093
Bernd Baumann
Edgar Serfling
Henning Walczak
Manfred Neumann
Martin Leverkus
Martin R Sprick
Matthias Goebeler
Thilo Mengling
Tina Wachter
P2860
P304
P356
10.1128/MCB.23.3.777-790.2003
P407
P577
2003-02-01T00:00:00Z