Mechanistic modeling of antigen sink effect for mavrilimumab following intravenous administration in patients with rheumatoid arthritis.
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Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and developmentReceptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical developmentPopulation Pharmacokinetics and Pharmacodynamics of Benralizumab in Healthy Volunteers and Patients With Asthma.Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritisDose-escalation of human anti-interferon-α receptor monoclonal antibody MEDI-546 in subjects with systemic sclerosis: a phase 1, multicenter, open label study.Mavrilimumab, a human monoclonal GM-CSF receptor-α antibody for the management of rheumatoid arthritis: a novel approach to therapy.Quantitative measurement of the target-mediated internalization kinetics of biopharmaceuticalsA mathematical analysis of rebound in a target-mediated drug disposition model: I.without feedback.Model-Based Discovery and Development of Biopharmaceuticals: A Case Study of Mavrilimumab.Efficacy and safety of mavrilimumab in Japanese subjects with rheumatoid arthritis: Findings from a Phase IIa study
P2860
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P2860
Mechanistic modeling of antigen sink effect for mavrilimumab following intravenous administration in patients with rheumatoid arthritis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Mechanistic modeling of antige ...... nts with rheumatoid arthritis.
@en
Mechanistic modeling of antige ...... nts with rheumatoid arthritis.
@nl
type
label
Mechanistic modeling of antige ...... nts with rheumatoid arthritis.
@en
Mechanistic modeling of antige ...... nts with rheumatoid arthritis.
@nl
prefLabel
Mechanistic modeling of antige ...... nts with rheumatoid arthritis.
@en
Mechanistic modeling of antige ...... nts with rheumatoid arthritis.
@nl
P2093
P2860
P356
P1476
Mechanistic modeling of antige ...... nts with rheumatoid arthritis.
@en
P2093
Fabio Magrini
Inna Vainshtein
Lorin Roskos
Matthew Sleeman
Meina Liang
Mikhail Zusmanovich
Yvonne Y Lau
P2860
P304
P356
10.1177/0091270011412964
P577
2011-09-23T00:00:00Z