Specific human granulocyte-macrophage colony-stimulating factor antagonists. - Wikidata - awgldk - TriplyDB

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

http://www.wikidata.org/entity/Q35536111

about

Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF Refined crystal structure and mutagenesis of human granulocyte-macrophage colony-stimulating factor Along the Axis between Type 1 and Type 2 Immunity; Principles Conserved in Evolution from Fish to Mammals Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three recepto Cytokines in asthma.D1 cap region involved in the receptor recognition and neural cell survival activity of human ciliary neurotrophic factor IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled.New approaches in the treatment of asthma.The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.A discontinuous eight-amino acid epitope in human interleukin-3 binds the alpha-chain of its receptor.A simplified method for the efficient refolding and purification of recombinant human GM-CSF Hematopoietic colony-stimulating factors: new players in tumor-nerve interactions.Regulation of haematopoiesis by growth factors - emerging insights and therapies.Protein engineering and preclinical development of a GM-CSF receptor antibody for the treatment of rheumatoid arthritis Saturation mutagenesis of human interleukin-3.Crystallization and preliminary X-ray diffraction analysis of the ternary human GM-CSF receptor complex.CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.Apoptosis of hemopoietic cells by the human granulocyte-macrophage colony-stimulating factor mutant E21R.The GM-CSF receptor family: mechanism of activation and implications for disease.DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells.Mechanistic modeling of antigen sink effect for mavrilimumab following intravenous administration in patients with rheumatoid arthritis.GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro.Hematopoietic Growth Factors and Blast Progenitors in Acute Leukemia.Construction and binding kinetics of a soluble granulocyte-macrophage colony-stimulating factor receptor alpha-chain-Fc fusion protein.An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M.Rational design of granulocyte-macrophage colony-stimulating factor antagonist peptides.Analysis of three human interleukin 5 structures suggests a possible receptor binding mechanism.A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all thr Molecular determinants of the granulocyte-macrophage colony-stimulating factor receptor complex assembly.Molecular modeling of the GM-CSF and IL-3 receptor complexes.An interleukin 5 mutant distinguishes between two functional responses in human eosinophils.Identification of an antigenic domain near the C terminus of human granulocyte-macrophage colony-stimulating factor and its spatial localization.The cell surface expression level of the human interleukin-5 receptor alpha subunit determines the agonistic/antagonistic balance of the human interleukin-5 E13Q mutein.Spatial Orientation of the α and βcReceptor Chain Binding Sites on Monomeric Human Interleukin-5 Constructs Cytokines: Principles and prospects Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Acts Independently of the Beta Common Subunit of the GM-CSF Receptor to Prevent Inner Cell Mass Apoptosis in Human Embryos1 Immunological and hematological effects of IL-5(Rα)-targeted therapy: An overview

P2860

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P2860

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

http://www.wikidata.org/entity/Q35536111

description

1994 nî lūn-bûn

@nan

1994 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1994年の論文

@ja

1994年論文

@yue

1994年論文

@zh-hant

1994年論文

@zh-hk

1994年論文

@zh-mo

1994年論文

@zh-tw

1994年论文

@wuu

name

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

@ast

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

@en

type

label

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

@ast

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

@en

prefLabel

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

@ast

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

@en

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PNAS.91.13.5838

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Specific human granulocyte-macrophage colony-stimulating factor antagonists

@en

P2093

B Cambareri

http://www.w3.org/2001/XMLSchema#string

C J Bagley

http://www.w3.org/2001/XMLSchema#string

M A Vadas

http://www.w3.org/2001/XMLSchema#string

M Dottore

http://www.w3.org/2001/XMLSchema#string

M F Shannon

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T R Hercus

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P2860

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor

A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

Ligand: a versatile computerized approach for characterization of ligand-binding systems

Supercoil sequencing: a fast and simple method for sequencing plasmid DNA

Human interleukin 4. The solution structure of a four-helix bundle protein.

Synovial fluid neutrophils of patients with rheumatoid arthritis have membrane antigen changes that reflect activation

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5838-5842

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scholarly article

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10.1073/PNAS.91.13.5838

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13

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91

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P50

Joanna M Woodcock

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1994-06-01T00:00:00Z

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15183321

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8016076

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44092

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