Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint.
about
Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damageBRCT domains: easy as one, two, threeGerminating fission yeast spores delay in G1 in response to UV irradiationFission yeast Rad26 responds to DNA damage independently of Rad3Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repairPhosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4TopBP1Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaksSite-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1Importance of a C-terminal conserved region of Chk1 for checkpoint function.Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases.Rad18 is required for DNA repair and checkpoint responses in fission yeast.The fission yeast Crb2/Chk1 pathway coordinates the DNA damage and spindle checkpoint in response to replication stress induced by topoisomerase I inhibitor.Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast.DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts.Redundant mechanisms prevent mitotic entry following replication arrest in the absence of Cdc25 hyper-phosphorylation in fission yeast.Fission yeast F-box protein Pof3 is required for genome integrity and telomere function.Fission yeast Rad26 is a regulatory subunit of the Rad3 checkpoint kinase.Mechanism of caffeine-induced checkpoint override in fission yeast.TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint.Genetic analyses of Schizosaccharomyces pombe dna2(+) reveal that dna2 plays an essential role in Okazaki fragment metabolism.Regulation of mitotic inhibitor Mik1 helps to enforce the DNA damage checkpointHistone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeastAnalysis of the fission yeast checkpoint Rad proteins.The DNA damage checkpoint and human cancer.Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-linksRegulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair.Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and Rad3 complexes.Critical Function of γH2A in S-PhaseEffects of BRCA1 transgene expression on murine mammary gland development and mutagen-induced mammary neoplasia.Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1Requirement of sequences outside the conserved kinase domain of fission yeast Rad3p for checkpoint control.Production of reactive oxygen species in response to replication stress and inappropriate mitosis in fission yeast.Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpointsRegulation of checkpoint kinases through dynamic interaction with Crb2.Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated.Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase IIIMitotic DNA damage and replication checkpoints in yeast.Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.
P2860
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P2860
Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Isolation and characterization ...... ot the replication checkpoint.
@en
Isolation and characterization ...... ot the replication checkpoint.
@nl
type
label
Isolation and characterization ...... ot the replication checkpoint.
@en
Isolation and characterization ...... ot the replication checkpoint.
@nl
prefLabel
Isolation and characterization ...... ot the replication checkpoint.
@en
Isolation and characterization ...... ot the replication checkpoint.
@nl
P2093
P2860
P356
P1476
Isolation and characterization ...... ot the replication checkpoint.
@en
P2093
P2860
P304
P356
10.1093/NAR/25.11.2138
P407
P577
1997-06-01T00:00:00Z