Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1
about
Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrestThe human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of BaxHuman SAD1 kinase is involved in UV-induced DNA damage checkpoint functionDNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free systemCdc25B functions as a novel coactivator for the steroid receptorsDamage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sitesActivation of the DNA damage checkpoint in mutants defective in DNA replication initiationDifferential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphataseThe human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilonFission yeast Rad26 responds to DNA damage independently of Rad3Mutation analysis of the CHK2 gene in breast carcinoma and other cancersFeedback loops and reciprocal regulation: recurring motifs in the systems biology of the cell cyclePds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint functionRetention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damageChecking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressorSCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphataseThe oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpointBlocking Chk1 expression induces apoptosis and abrogates the G2 checkpoint mechanismThe oxidative stress responsive transcription factor Pap1 confers DNA damage resistance on checkpoint-deficient fission yeast cellsCell cycle checkpoint regulators reach a zillion.Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override.Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach.Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism.The fission yeast DNA structure checkpoint protein Rad26ATRIP/LCD1/UVSD accumulates in the cytoplasm following microtubule destabilizationFission yeast Rad17 associates with chromatin in response to aberrant genomic structuresBasis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases.Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.Rad18 is required for DNA repair and checkpoint responses in fission yeast.Reovirus-induced sigma1s-dependent G(2)/M phase cell cycle arrest is associated with inhibition of p34(cdc2).Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast.DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts.Redundant mechanisms prevent mitotic entry following replication arrest in the absence of Cdc25 hyper-phosphorylation in fission yeast.Mechanism of caffeine-induced checkpoint override in fission yeast.Roles of the mitotic inhibitors Wee1 and Mik1 in the G(2) DNA damage and replication checkpoints.Cell cycle checkpoints and their inactivation in human cancer.Natural meiotic recombination hot spots in the Schizosaccharomyces pombe genome successfully predicted from the simple sequence motif M26mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phase
P2860
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P2860
Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1
@en
type
label
Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1
@en
prefLabel
Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1
@en
P2093
P2860
P356
P1476
Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1
@en
P2093
P2860
P304
P356
10.1091/MBC.10.4.833
P577
1999-04-01T00:00:00Z