Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutagenic in human cells.
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Reductive activation with cysteine represents a chromium(III)-dependent pathway in the induction of genotoxicity by carcinogenic chromium(VI).Metabolic pathways of carcinogenic chromium.Fanconi anemia complementation group A cells are hypersensitive to chromium(VI)-induced toxicity.Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromiumChromium reduces the in vitro activity and fidelity of DNA replication mediated by the human cell DNA synthesome.Monitoring Cr intermediates and reactive oxygen species with fluorescent probes during chromate reduction.Mismatch repair proteins are activators of toxic responses to chromium-DNA damage.Zinc chromate induces chromosome instability and DNA double strand breaks in human lung cells.Excision repair is required for genotoxin-induced mutagenesis in mammalian cells.Chromate-induced sulfur starvation and mRNA mistranslation in yeast are linked in a common mechanism of Cr toxicityEnhanced exopolymer production and chromium stabilization in Pseudomonas putida unsaturated biofilmsTrivalent chromium: assessing the genotoxic risk of an essential trace element and widely used human and animal nutritional supplement.Utilization of DNA-protein cross-links as a biomarker of chromium exposureChromium(VI) causes interstrand DNA cross-linking in vitro but shows no hypersensitivity in cross-link repair-deficient human cellsAirborne particulate metals in the New York City subway: a pilot study to assess the potential for health impacts.Chromium in drinking water: sources, metabolism, and cancer risksMetabolism of Cr(VI) by ascorbate but not glutathione is a low oxidant-generating process.Toxicity and carcinogenicity of chromium compounds in humans.Reduction with glutathione is a weakly mutagenic pathway in chromium(VI) metabolismMolecular mechanisms of hexavalent chromium-induced apoptosis in human bronchoalveolar cellsRole of direct reactivity with metals in chemoprotection by N-acetylcysteine against chromium(VI), cadmium(II), and cobalt(II).The role of oxidative stress in carcinogenesis induced by metals and xenobiotics.DNA polymerase zeta is essential for hexavalent chromium-induced mutagenesis.Molecular mechanisms of Cr(VI) resistance in bacteria and fungi.Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adductsIntracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity.Rapid DNA double-strand breaks resulting from processing of Cr-DNA cross-links by both MutS dimers.Human nucleotide excision repair efficiently removes chromium-DNA phosphate adducts and protects cells against chromate toxicity.Ethnopharmacological Approaches for Therapy of Jaundice: Part IEffect of chromate stress on Escherichia coli K-12.Derivation and study of human epithelial cell lines resistant to killing by chromium trioxide.Safety and efficacy of chromium methionine (Availa® Cr) as feed additive for all speciesScientific Opinion on the risks to public health related to the presence of chromium in food and drinking waterFormation and repair of DNA-protein crosslink damage.Comparative Proteomics of Chromium-Transformed Beas-2B Cells by 2D-DIGE and MALDI-TOF/TOF MS.Importance of ligand structure in DNA/protein binding, mutagenicity, excision repair and nutritional aspects of chromium(III) complexes.
P2860
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P2860
Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutagenic in human cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Cr(III)-mediated crosslinks of ...... are mutagenic in human cells.
@en
type
label
Cr(III)-mediated crosslinks of ...... are mutagenic in human cells.
@en
prefLabel
Cr(III)-mediated crosslinks of ...... are mutagenic in human cells.
@en
P2093
P2860
P356
P1476
Cr(III)-mediated crosslinks of ...... are mutagenic in human cells.
@en
P2093
P2860
P304
P356
10.1093/NAR/26.8.2024
P407
P577
1998-04-01T00:00:00Z