Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitis
about
Gamma-herpesvirus latency requires T cell evasion during episome maintenanceInterference of hepatitis C virus RNA replication by short interfering RNAsDual GPCR and GAG mimicry by the M3 chemokine decoy receptorInhibition of chemokine-glycosaminoglycan interactions in donor tissue reduces mouse allograft vasculopathy and transplant rejectionIdentification of candidate gammaherpesvirus 68 genes required for virus replication by signature-tagged transposon mutagenesis.A single CD8+ T cell epitope sets the long-term latent load of a murid herpesvirusVirus-encoded microRNAs facilitate gammaherpesvirus latency and pathogenesis in vivoPathogenesis of a model gammaherpesvirus in a natural hostCharacterization of a novel wood mouse virus related to murid herpesvirus 4.Identification of proteins associated with murine gammaherpesvirus 68 virions.Construction and characterization of an infectious murine gammaherpesivrus-68 bacterial artificial chromosome.Murine gammaherpesvirus 68 lacking thymidine kinase shows severe attenuation of lytic cycle replication in vivo but still establishes latencyChemokine binding protein M3 of murine gammaherpesvirus 68 modulates the host response to infection in a natural hostProteomic characterization of murid herpesvirus 4 extracellular virionsSelective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes.Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract.Retention of anergy and inhibition of antibody responses during acute γ herpesvirus 68 infectionViral strategies for evading antiviral cellular immune responses of the host.A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology.The limits of protection by "memory" T cells in Ig-/- mice persistently infected with a gamma-herpesvirusEstablishment of B-cell lines latently infected with reactivation-competent murine gammaherpesvirus 68 provides evidence for viral alteration of a DNA damage-signaling cascade.The m4 gene of murine gammaherpesvirus modulates productive and latent infection in vivo.Virtual screening of m3 protein antagonists for finding a model to study the gammaherpesvirus damaged immune system and chemokine related diseases.Pervasive transcription of a herpesvirus genome generates functionally important RNAs.Evasion of adaptive and innate immune response mechanisms by γ-herpesviruses.Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor.Disruption of CCL21-induced chemotaxis in vitro and in vivo by M3, a chemokine-binding protein encoded by murine gammaherpesvirus 68.Effective vaccination against long-term gammaherpesvirus latency.Use of a virus-encoded enzymatic marker reveals that a stable fraction of memory B cells expresses latency-associated nuclear antigen throughout chronic gammaherpesvirus infection.The gammaherpesvirus chemokine binding protein binds to the N terminus of CXCL8.T-cell responses to the M3 immune evasion protein of murid gammaherpesvirus 68 are partially protective and induced with lytic antigen kinetics.An internal ribosome entry site directs translation of the murine gammaherpesvirus 68 MK3 open reading frame.Murine gammaherpesvirus 68 open reading frame 45 plays an essential role during the immediate-early phase of viral replication.Murine gammaherpesvirus 68 glycoprotein 150 does not contribute to latency amplification in vivo.A web interface for easy flexible protein-protein docking with ATTRACTDisruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier.
P2860
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P2860
Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitis
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
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2002年學術文章
@zh-hant
name
Critical role for a high-affin ...... irus-induced lethal meningitis
@en
Critical role for a high-affin ...... rus-induced lethal meningitis.
@nl
type
label
Critical role for a high-affin ...... irus-induced lethal meningitis
@en
Critical role for a high-affin ...... rus-induced lethal meningitis.
@nl
prefLabel
Critical role for a high-affin ...... irus-induced lethal meningitis
@en
Critical role for a high-affin ...... rus-induced lethal meningitis.
@nl
P2093
P2860
P356
P1476
Critical role for a high-affin ...... irus-induced lethal meningitis
@en
P2093
Beth Levine
James E Goldman
Samuel H Speck
Sharookh B Kapadia
Victor van Berkel
P2860
P304
P356
10.1172/JCI14358
P407
P577
2002-04-01T00:00:00Z