Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.
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Mechanisms of gene regulation by fatty acidsSterol Regulatory Element-Binding Proteins (SREBP) signallingFish oil and krill oil supplementations differentially regulate lipid catabolic and synthetic pathways in mice.Esterase 1 is a novel transcriptional repressor of growth hormone receptor gene expression: a unique noncatalytic role for a carboxyesterase protein.The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage has impaired glucose tolerance independent of body weight.Linoleic and α-linolenic fatty acid consumption over three generations exert cumulative regulation of hepatic expression of genes related to lipid metabolism.Group X secretory phospholipase A2 negatively regulates adipogenesis in murine modelsDifferent Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice.Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system.The Niemann-Pick C1 gene is downregulated in livers of C57BL/6J mice by dietary fatty acids, but not dietary cholesterol, through feedback inhibition of the SREBP pathway.KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.Elaidic acid increases hepatic lipogenesis by mediating sterol regulatory element binding protein-1c activity in HuH-7 cells.A pathway approach to investigate the function and regulation of SREBPs.Effects of short- and long-chain fatty acids on the expression of stearoyl-CoA desaturase and other lipogenic genes in bovine mammary epithelial cells.n-3 Polyunsaturated Fatty Acids and Metabolic Syndrome Risk: A Meta-Analysis.Omega-3 fatty acids: Mechanisms of benefit and therapeutic effects in pediatric and adult NAFLD.Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes.Perinatal maternal high-fat diet promotes alterations in hepatic lipid metabolism and resistance to the hypolipidemic effect of fish oil in adolescent rat offspring.Coordinate Regulation of Yeast Sterol Regulatory Element-binding Protein (SREBP) and Mga2 Transcription Factors.A novel processing system of sterol regulatory element-binding protein-1c regulated by polyunsaturated fatty acid.4'-Hydroxyflavanone suppresses activation of sterol regulatory element-binding proteins and de novo lipid synthesis.A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.Developmental Programming of Nonalcoholic Fatty Liver Disease: The Effect of Early Life Nutrition on Susceptibility and Disease Severity in Later Life.Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity: a pilot study.Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization.Peroxisome proliferator-activated receptor alpha target genes.Binding of polyunsaturated fatty acids to LXRα and modulation of SREBP-1 interaction with a specific SCD1 promoter element.The compositional and metabolic responses of gilthead seabream (Sparus aurata) to a gradient of dietary fish oil and associated n-3 long-chain PUFA content.Standardisation of the Japanese diet for use in animal experiments.SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.Genomics of lactation: role of nutrigenomics and nutrigenetics in the fatty acid composition of human milk.Probiotics Supplemented with Omega-3 Fatty Acids are More Effective for Hepatic Steatosis Reduction in an Animal Model of Obesity.Chronic dietary n-3 PUFA intervention improves dyslipidaemia and subsequent cardiovascular complications in the JCR:LA- cp rat model of the metabolic syndrome.Sterol Metabolism and Transport in Atherosclerosis and Cancer
P2860
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P2860
Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Polyunsaturated fatty acids se ...... d autoloop regulatory circuit.
@en
Polyunsaturated fatty acids se ...... d autoloop regulatory circuit.
@nl
type
label
Polyunsaturated fatty acids se ...... d autoloop regulatory circuit.
@en
Polyunsaturated fatty acids se ...... d autoloop regulatory circuit.
@nl
prefLabel
Polyunsaturated fatty acids se ...... d autoloop regulatory circuit.
@en
Polyunsaturated fatty acids se ...... d autoloop regulatory circuit.
@nl
P2093
P2860
P356
P1476
Polyunsaturated fatty acids se ...... nd autoloop regulatory circuit
@en
P2093
Hitoshi Shimano
Jun-ichi Osuga
Kazunori Kataoka
Keiji Itaka
Ken Ohashi
Makiko Nishi
Midori Kubota
Motohiro Sekiya
Nobuhiro Yamada
Ryozo Nagai
P2860
P304
11681-11691
P356
10.1074/JBC.M109.096107
P407
P50
P577
2010-02-09T00:00:00Z