about
Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liverGranuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic miceEarly embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase geneIdentification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysisAcetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy statusSterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genesAsialoglycoprotein receptor deficiency in mice lacking the major receptor subunit. Its obligate requirement for the stable expression of oligomeric receptor.FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivoSREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity.Circulating malondialdehyde-modified LDL-related variables and coronary artery stenosis in asymptomatic patients with type 2 diabetesInhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance.Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice.Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model.Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 systemKLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice.Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis.Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements.Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor.p53 involvement in the pathogenesis of fatty liver disease.Hepatic Control of Energy Metabolism via the Autonomic Nervous System.Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.[A case of fatal pneumonia caused by Legionella pneumophila serogroup 6 developed after drowning in a public bath].Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets.Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.
P50
Q28243492-6A89EF28-F975-4B41-8D5A-4CFD81A95CE3Q28505447-33AA721F-EA44-48FE-97E8-B584C320B5AFQ28585227-F3331918-476E-42D9-9611-DE97F2A3FB9FQ28585748-B48FE9A6-DB3E-4C06-8C95-AB5FA718ADECQ28586350-83296974-3FCD-41FD-9056-540BD648637BQ28646399-E6A2A402-B9D0-4E0A-B74E-C4623A79A7EBQ30661651-9291DE7C-ED2B-4667-A970-E835B7959725Q30873486-55B68E6D-87CA-4CEB-9593-B743F27F8612Q31415275-F79B224D-6023-4C52-921C-204DAA5A9842Q32085397-8263AABE-7251-4CEE-B7C9-F306BD737703Q33220241-89BEE798-82CC-4256-96C5-7310674D6DD8Q33760162-92341D09-E375-44BB-A57E-D621EDBCB1B6Q34289658-D8325520-FCF4-4B08-BA66-5C708A1897E5Q34977813-6178524D-53E2-421E-919D-DBC360B70B5CQ35341724-48719245-D8B6-4038-B9F3-B803430702C7Q35562476-F349A01F-2F1D-4D6E-9CB9-E3C5306B7E58Q35674559-C1B1ADCA-EB4D-4120-A117-D95C32796173Q36059065-2DC6015E-88E3-448E-A6C2-06BC21F2303DQ36333590-E220C9C6-5F36-4D3B-BAEE-26678D96C7D1Q36996099-E6BD9C8F-9F86-4167-AE8B-3109C73D5723Q37273150-F495A0E3-A1EC-4FCE-8C1B-4BEB24707DDFQ37368738-4BF611BC-95D7-45C6-A559-55C6D25CFE7BQ37394060-E83941E4-E31B-4C98-AD69-64317AD44E6DQ38288889-0563D33E-FE73-456F-95AE-9926B5BAE844Q38290977-68F6A9D5-5462-4E25-8FAE-23B3253BB2D9Q38295025-85CB7BC4-93A6-4B97-B314-02A3B83A1BEDQ38297724-494D8253-D226-4E70-9E6D-365BE9BD1E6EQ38299150-ABCF8FCC-45E3-44A6-971F-4BF21A9ABEF2Q38344355-FDEFD71E-7BFA-4BB7-B3AB-E3261138924AQ38945898-AB9D9C2C-A151-4FC8-8C89-F505EE301D05Q39022770-5264F241-50E7-4829-B479-CCE1B4BD104AQ39232444-D487C8F4-0CFE-45D8-945D-DA2D97FC4436Q39735993-2569D7F6-2EC2-4CA3-B805-DF62F64EE246Q39741460-428A3B2D-F357-44E6-9709-D6A6CD92D89DQ40298483-12AC50E6-4BD3-4E9F-9E74-5C29C1006952Q40655916-7E682A22-93DE-467C-94CE-E166FF0BD983Q40728683-7C596F5F-D33E-496E-8EDE-4F7B17764976Q41965207-D3BC3B3C-74ED-4412-8C90-0403E0BA1E20Q42403132-6A2FB11B-63E2-4C21-9646-32B8BB8C4B4DQ42440719-867F9D76-A895-4B46-8CAE-2B23A7D62097
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Naoya Yahagi
@ast
Naoya Yahagi
@en
Naoya Yahagi
@es
Naoya Yahagi
@nl
Naoya Yahagi
@sl
type
label
Naoya Yahagi
@ast
Naoya Yahagi
@en
Naoya Yahagi
@es
Naoya Yahagi
@nl
Naoya Yahagi
@sl
prefLabel
Naoya Yahagi
@ast
Naoya Yahagi
@en
Naoya Yahagi
@es
Naoya Yahagi
@nl
Naoya Yahagi
@sl
P1053
D-2360-2014
P106
P1153
7006607036
P21
P31
P3829
P496
0000-0002-1823-1865
P569
2000-01-01T00:00:00Z