Error-prone polymerase, DNA polymerase IV, is responsible for transient hypermutation during adaptive mutation in Escherichia coli.
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Inhibition of mutation and combating the evolution of antibiotic resistanceA strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coliError-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli.Mutator phenotype resulting from DNA polymerase IV overproduction in Escherichia coli: preferential mutagenesis on the lagging strand.Characterization of three mycobacterial DinB (DNA polymerase IV) paralogs highlights DinB2 as naturally adept at ribonucleotide incorporation.Translesion DNA polymerasesTranslesion DNA Synthesis.Amplification of lac cannot account for adaptive mutation to Lac+ in Escherichia coli.Aeons of distress: an evolutionary perspective on the bacterial SOS response.Escherichia coli Rep DNA helicase and error-prone DNA polymerase IV interact physically and functionallyRole of DNA polymerase IV in Escherichia coli SOS mutator activityRole of Escherichia coli DNA polymerase IV in in vivo replication fidelityDouble-Strand Break Repair and Holliday Junction Processing Are Required for Chromosome Processing in Stationary-Phase Escherichia coli CellsAdaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number.Interactions and Localization of Escherichia coli Error-Prone DNA Polymerase IV after DNA Damage.Stress responses and genetic variation in bacteria.Mutation of DNA polymerase beta in esophageal carcinoma of different regionsBacterial stationary-state mutagenesis and Mammalian tumorigenesis as stress-induced cellular adaptations and the role of epigenetics.Adaptive mutation: general mutagenesis is not a programmed response to stress but results from rare coamplification of dinB with lac.Controlling mutation: intervening in evolution as a therapeutic strategy.Stress-induced mutagenesis in bacteria.DNA polymerase switching: effects on spontaneous mutagenesis in Escherichia coliRole of polyphosphates in microbial adaptation to extreme environmentsSteric gate variants of UmuC confer UV hypersensitivity on Escherichia coli.Bacteria as computers making computers.Polymerases leave fingerprints: analysis of the mutational spectrum in Escherichia coli rpoB to assess the role of polymerase IV in spontaneous mutation.Multiple strategies for translesion synthesis in bacteriaMapping DNA polymerase errors by single-molecule sequencing.Prevalence of season-specific Escherichia coli strains in the Yeongsan River Basin of South Korea.Stress-Induced Mutagenesis.SOS-independent induction of dinB transcription by beta-lactam-mediated inhibition of cell wall synthesis in Escherichia coli.Adaptive point mutation and adaptive amplification pathways in the Escherichia coli Lac system: stress responses producing genetic changeThe optimal burst of mutation to create a phenotype.UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB.Involvement of Escherichia coli DNA polymerase IV in tolerance of cytotoxic alkylating DNA lesions in vivo.Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies.Mismatch repair modulation of MutY activity drives Bacillus subtilis stationary-phase mutagenesis.Metabolic and evolutionary patterns in the extremely acidophilic archaeon Ferroplasma acidiphilum YT.A ΔdinB mutation that sensitizes Escherichia coli to the lethal effects of UV- and X-radiation.Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication.
P2860
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P2860
Error-prone polymerase, DNA polymerase IV, is responsible for transient hypermutation during adaptive mutation in Escherichia coli.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
Error-prone polymerase, DNA po ...... mutation in Escherichia coli.
@en
Error-prone polymerase, DNA po ...... mutation in Escherichia coli.
@nl
type
label
Error-prone polymerase, DNA po ...... mutation in Escherichia coli.
@en
Error-prone polymerase, DNA po ...... mutation in Escherichia coli.
@nl
prefLabel
Error-prone polymerase, DNA po ...... mutation in Escherichia coli.
@en
Error-prone polymerase, DNA po ...... mutation in Escherichia coli.
@nl
P2093
P2860
P1476
Error-prone polymerase, DNA po ...... e mutation in Escherichia coli
@en
P2093
Jeffrey D Stumpf
Jennifer L Nelson
Jill C Hazel
Joshua D Tompkins
Stacy L Leugers
P2860
P304
P356
10.1128/JB.185.11.3469-3472.2003
P407
P577
2003-06-01T00:00:00Z