Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
about
Infectious rotavirus enters cells by direct cell membrane penetration, not by endocytosisRotavirus infection reduces sucrase-isomaltase expression in human intestinal epithelial cells by perturbing protein targeting and organization of microvillar cytoskeleton.Rotavirus structural proteins and dsRNA are required for the human primary plasmacytoid dendritic cell IFNalpha responseViruses and cells with mutations affecting viral entry are selected during persistent rotavirus infections of MA104 cellsAttachment and growth of human rotaviruses RV-3 and S12/85 in Caco-2 cells depend on VP4.Integrins alpha2beta1 and alpha4beta1 can mediate SA11 rotavirus attachment and entry into cells.The VP5 domain of VP4 can mediate attachment of rotaviruses to cells.Primary murine small intestinal epithelial cells, maintained in long-term culture, are susceptible to rotavirus infection.Proteolysis of monomeric recombinant rotavirus VP4 yields an oligomeric VP5* coreStructural correlates of rotavirus cell entry.Requirement for vacuolar H+ -ATPase activity and Ca2+ gradient during entry of rotavirus into MA104 cellsInteraction of rotaviruses with Hsc70 during cell entry is mediated by VP5New insights into rotavirus entry machinery: stabilization of rotavirus spike conformation is independent of trypsin cleavage.Cross-linking of rotavirus outer capsid protein VP7 by antibodies or disulfides inhibits viral entryMonkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunitInfectious subvirion particles of reovirus type 3 Dearing exhibit a loss in infectivity and contain a cleaved sigma 1 proteinGenetic mapping indicates that VP4 is the rotavirus cell attachment protein in vitro and in vivo.Trypsin activation pathway of rotavirus infectivity.Rotavirus is released from the apical surface of cultured human intestinal cells through nonconventional vesicular transport that bypasses the Golgi apparatus.Isolation and identification of group A rotaviruses among neonatal diarrheic calves, Morocco.Culturing, storage, and quantification of rotaviruses.Three-dimensional structure of rhesus rotavirus by cryoelectron microscopy and image reconstructionModeling of the rotavirus group C capsid predicts a surface topology distinct from other rotavirus speciesNorovirus capture with histo-blood group antigens reveals novel virus-ligand interactions.Rotaviruses induce an early membrane permeabilization of MA104 cells and do not require a low intracellular Ca2+ concentration to initiate their replication cycle.The spike protein VP4 defines the endocytic pathway used by rotavirus to enter MA104 cells.Physical and chemical methods for enhancing rapid detection of viruses and other agents.Interaction of rotavirus particles with liposomes.Rotavirus YM gene 4: analysis of its deduced amino acid sequence and prediction of the secondary structure of the VP4 protein.Rotavirus contains integrin ligand sequences and a disintegrin-like domain that are implicated in virus entry into cells.Intraluminal proteolytic activation plays an important role in replication of type 1 reovirus in the intestines of neonatal mice.Polypeptide composition of rotavirus empty capsids and their possible use as a subunit vaccine.Priming for rotavirus neutralizing antibodies by a VP4 protein-derived synthetic peptideRole of VP3 in human rotavirus internalization after target cell attachment via VP7.Purification and characterization of bovine rotavirus cores.Rotavirus gene structure and function.VP7 mediates the interaction of rotaviruses with integrin alphavbeta3 through a novel integrin-binding site.Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences.Three-dimensional structure of the rotavirus haemagglutinin VP4 by cryo-electron microscopy and difference map analysis.Rotaviruses reach late endosomes and require the cation-dependent mannose-6-phosphate receptor and the activity of cathepsin proteases to enter the cell.
P2860
Q27486809-1BB3BAE5-D943-415D-A57F-06D1B5228AF4Q32041827-42CF499E-F979-4A8C-9173-4CE824A061E6Q33598425-305960C6-BA3D-4ACE-A7CE-FBB1E604A5F8Q33783122-D8C26747-FCA5-4F04-8C8C-15D52EBE8066Q33785499-D7F2665C-F1ED-4F49-902F-A7173FA9FB98Q33794692-FE994FBB-8CC3-48E0-81FB-F2E3CB752C10Q33795796-86463833-2EA1-48AB-8E6D-F5BBE8612761Q33805811-C6FD5DA3-9E2C-4D74-B931-D0E7D279DF5AQ33852569-2DC8E9BB-3861-4893-9B8F-3C4716C71BA8Q34166434-3D3267FC-A617-457C-A12A-EE4609C58635Q34351223-C8C2C29E-AC7E-4B3F-8047-13CF30034BA3Q35149035-2AAAF44C-8AD3-404B-A387-9DD46CE116FBQ35175745-697B8ED2-AA2A-4B25-AF63-97EE674AB980Q35275131-E43E0B54-C7CF-4743-A7CC-515AC50FA3DFQ35802730-2255624A-2A1C-4E0C-9975-9EE49C40A7DAQ35845209-E29D9706-5F81-4727-90A1-58D48D4D9244Q35853803-025E2AE5-BA14-4D7B-90BC-6E985265A94DQ35867736-05490CD3-3EEC-499D-991A-C1952A11CC5FQ35898075-8D15B1F7-4EA1-4A48-9E6C-17E9009620AAQ36009955-B71FB15F-70C7-4F4F-BDF4-CDF96AEBE529Q36112065-069783EA-E7BF-4CAB-9799-F000171BD2ACQ36223160-50CAD9C0-BD6D-4F2E-8722-6F2065869708Q36373266-0E50C3B0-CCCA-46F1-B2B3-B34D58312965Q36510326-70851395-75EC-4CF5-8F32-C1546075BC44Q36548599-D9B9DD47-DAD5-4C5D-AD02-B17609394D5AQ36559900-187D3DD3-ABC6-40BE-AAAB-CCB5353FC35AQ36639842-A25129C8-44A6-463E-95FD-F07A537F9AC7Q36697893-6B47382C-D01F-4CF5-9B33-3A85504CB16AQ36701430-BD71FAD9-2408-4E02-8752-730F5B469C4AQ36773071-80A2FF55-2E19-4FF3-AAD1-F176D1C02146Q36804334-1D64DAAA-AAD4-40BF-9D51-CBB80B8E6D35Q36811869-DD01F90B-FF06-4F13-91EE-4EBAFA4CED6CQ36832392-955BD043-6980-499B-B876-ADEA09077386Q36871036-053144A8-95D2-4485-9981-025C8DAA6B7DQ36924461-82BF032B-0E81-4608-942F-A72C6E4E617EQ37055891-0FB401A5-B900-44D5-A758-546AB30375C4Q37567855-B75CD5BF-816E-4619-88A8-F26040CC086DQ37583524-0912C522-B386-4251-B9A1-DCC68A1BE286Q37629295-3811FF6F-863D-47FB-85BE-5CF6627EBD01Q37713871-C968EFAC-FD3E-411A-BF9D-217595CF3E48
P2860
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
@yue
1981年學術文章
@zh
1981年學術文章
@zh-hant
name
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
@en
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
@nl
type
label
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
@en
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
@nl
prefLabel
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
@en
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
@nl
P2093
P2860
P1433
P1476
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
@en
P2093
P2860
P304
P407
P577
1981-09-01T00:00:00Z