TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II - Wikidata - awgldk - TriplyDB

TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II

TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II

http://www.wikidata.org/entity/Q39814573

about

Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B Human mediator subunit MED26 functions as a docking site for transcription elongation factors Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF)Mutual relationships between transcription and pre-mRNA processing in the synthesis of mRNA Gene-specific requirement of RNA polymerase II CTD phosphorylation Coupling pre-mRNA processing to transcription on the RNA factory assembly line A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72 The structure and substrate specificity of human Cdk12/Cyclin K RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex.Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes.Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template Progression through the RNA polymerase II CTD cycle Site-specific regulation of histone H1 phosphorylation in pluripotent cell differentiation Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos RNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases.CDK8 is a positive regulator of transcriptional elongation within the serum response network.On the traces of XPD: cell cycle matters - untangling the genotype-phenotype relationship of XPD mutations The RNA polymerase II CTD coordinates transcription and RNA processing.RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts.RNA polymerase II CTD modifications: how many tales from a single tail.Targeting transcription regulation in cancer with a covalent CDK7 inhibitor CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer.CDK7-dependent transcriptional addiction in triple-negative breast cancer.B2 RNA represses TFIIH phosphorylation of RNA polymerase II.CDK8: a positive regulator of transcription Coupling mRNA synthesis and decay.Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation.The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors.RNA polymerase II transcription elongation control.

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P2860

TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II

http://www.wikidata.org/entity/Q39814573

description

2009 nî lūn-bûn

@nan

2009年の論文

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2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

TFIIH-associated Cdk7 kinase f ...... rmination by RNA polymerase II

@en

TFIIH-associated Cdk7 kinase f ...... mination by RNA polymerase II.

@nl

type

label

TFIIH-associated Cdk7 kinase f ...... rmination by RNA polymerase II

@en

TFIIH-associated Cdk7 kinase f ...... mination by RNA polymerase II.

@nl

prefLabel

TFIIH-associated Cdk7 kinase f ...... rmination by RNA polymerase II

@en

TFIIH-associated Cdk7 kinase f ...... mination by RNA polymerase II.

@nl

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P1433

Molecular and Cellular Biology

P1476

TFIIH-associated Cdk7 kinase f ...... rmination by RNA polymerase II

@en

P2093

Benjamin Erickson

http://www.w3.org/2001/XMLSchema#string

Chao Zhang

http://www.w3.org/2001/XMLSchema#string

Kevan Shokat

http://www.w3.org/2001/XMLSchema#string

Robert P Fisher

http://www.w3.org/2001/XMLSchema#string

Stéphane Larochelle

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P2860

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

Cdk-activating kinase complex is a component of human transcription factor TFIIH

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation

Pause sites promote transcriptional termination of mammalian RNA polymerase II

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor

The role of chromatin during transcription

TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II.

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

Controlling the elongation phase of transcription with P-TEFb

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5455-5464

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scholarly article

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10.1128/MCB.00637-09

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20

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29

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Kira Glover-Cutter

Stéphane Larochelle

David L Bentley

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2009-08-10T00:00:00Z

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26728922

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P698

19667075

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P921

phosphorylation

P932

2756882

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