Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.
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GPCR oligomers in pharmacology and signalingDopamine D4 receptor oligomerization--contribution to receptor biogenesisMolecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) couplingThe tetrahydroisoquinoline derivative SB269,652 is an allosteric antagonist at dopamine D3 and D2 receptorsDistinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein couplingAllostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapesEvidence against dopamine D1/D2 receptor heteromers.Dimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced DissociationCrystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal stateStructure and functional interaction of the extracellular domain of human GABAB receptor GBR2Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor ComplexesHeteroreceptor Complexes and their Allosteric Receptor-Receptor Interactions as a Novel Biological Principle for Integration of Communication in the CNS: Targets for Drug DevelopmentA new mechanism of allostery in a G protein-coupled receptor dimerA functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2Dopamine receptors - IUPHAR Review 13Adenosine-cannabinoid receptor interactions. Implications for striatal functionStriatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonistsLigand-directed functional selectivity at the mu opioid receptor revealed by label-free integrative pharmacology on-targetCharacterisation of the interaction of the C-terminus of the dopamine D2 receptor with neuronal calcium sensor-1Dopamine receptor activation increases HIV entry into primary human macrophagesTrans-activation between 7TM domains: implication in heterodimeric GABAB receptor activationStructure-guided development of heterodimer-selective GPCR ligandsFunctional characterization of G-protein-coupled receptors: a bioinformatics approach.Investigation of D₂ receptor-agonist interactions using a combination of pharmacophore and receptor homology modeling.Membrane driven spatial organization of GPCRs.Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptorsSegregation of family A G protein-coupled receptor protomers in the plasma membraneCalcium-mediated modulation of the quaternary structure and function of adenosine A2A-dopamine D2 receptor heteromersIncreasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation.Leukotriene BLT2 receptor monomers activate the G(i2) GTP-binding protein more efficiently than dimersOligomerization of G-protein-coupled receptors: a realityAn in vivo demonstration of functional G protein-coupled receptor dimers.Not just an oil slick: how the energetics of protein-membrane interactions impacts the function and organization of transmembrane proteins.Polyamidoamine (PAMAM) dendrimer conjugates of "clickable" agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide.Internalization dissociates β2-adrenergic receptorsContribution of mu and delta opioid receptors to the pharmacological profile of kappa opioid receptor subtypes.Dominant negative actions of human prostacyclin receptor variant through dimerization: implications for cardiovascular disease.Importance of lipid-exposed residues in transmembrane segment four for family B calcitonin receptor homo-dimerization.Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers.The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Gαi proteins, and constitutively impairs CXCR4 functioning.
P2860
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P2860
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Allosteric communication betwe ...... R dimers modulates activation.
@en
Allosteric communication betwe ...... R dimers modulates activation.
@nl
type
label
Allosteric communication betwe ...... R dimers modulates activation.
@en
Allosteric communication betwe ...... R dimers modulates activation.
@nl
prefLabel
Allosteric communication betwe ...... R dimers modulates activation.
@en
Allosteric communication betwe ...... R dimers modulates activation.
@nl
P2860
P50
P356
P1476
Allosteric communication betwe ...... CR dimers modulates activation
@en
P2093
Eneko Urizar
P2860
P2888
P304
P356
10.1038/NCHEMBIO.199
P577
2009-08-02T00:00:00Z