Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
about
Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumorsIslet amyloid in type 2 diabetes, and the toxic oligomer hypothesisPancreatic β Cell Mass DeathCausative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitusHyaluronan: A Mediator of Islet Dysfunction and Destruction in Diabetes?Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?Changes in beta cell function occur in prediabetes and early disease in the Lepr (db) mouse model of diabetes.Defect of insulin signal in peripheral tissues: Important role of ceramideNatural history of β-cell adaptation and failure in type 2 diabetesICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATsPancreatic beta cells lack a low glucose and O2-inducible mitochondrial protein that augments cell survivalTcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell lineCalcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosisPositional cloning of "Lisch-Like", a candidate modifier of susceptibility to type 2 diabetes in miceAdult tissue sources for new β cells.Obesity and type 2 diabetes: what can be unified and what needs to be individualized?Spatiotemporal Dynamics of Insulitis in Human Type 1 DiabetesPancreatic β-cell proliferation in obesity.Protective effect of quercetin on the morphology of pancreatic beta-cells of streptozotocin-treated diabetic ratsSlow and steady is the key to beta-cell replication.Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1Current status of islet cell replacement and regeneration therapy.Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodentsIs the diminished incretin effect in type 2 diabetes just an epi-phenomenon of impaired beta-cell function?Unique arrangement of alpha- and beta-cells in human islets of LangerhansIncreased ectodomain shedding of cell adhesion molecule 1 from pancreatic islets in type 2 diabetic pancreata: correlation with hemoglobin A1c levels.Postnatal development of numbers and mean sizes of pancreatic islets and beta-cells in healthy mice and GIPR(dn) transgenic diabetic mice.Pathologic changes and glucose homeostasis according to expression of human islet amyloid polypeptide in type 2 diabetic patientsFLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication.Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitusAssay development and multivariate scoring for high-content discovery of chemoprotectants of endoplasmic-reticulum-stress-mediated amylin-induced cytotoxicity in pancreatic beta cellsAge-related impairment of pancreatic Beta-cell function: pathophysiological and cellular mechanisms.FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survivalβ-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency.Erectile dysfunction in young non-obese type II diabetic Goto-Kakizaki rats is associated with decreased eNOS phosphorylation at Ser1177Characterization of β-cell plasticity mechanisms induced in mice by a transient source of exogenous insulin.Pancreatic alpha cell mass in European subjects with type 2 diabetesRecent progress in studies of factors that elicit pancreatic β-cell expansionβ-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition.
P2860
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P2860
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
@en
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
@nl
type
label
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
@en
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
@nl
prefLabel
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
@en
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
@nl
P2093
P921
P1476
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited
@en
P2093
P304
P577
1985-01-01T00:00:00Z