Mechanism of action of species-selective P2X(7) receptor antagonists.
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P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microgliaAn Improved Method for P2X7R Antagonist ScreeningPositive allosteric modulation by ivermectin of human but not murine P2X7 receptorsThe Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus.Functional identification of close proximity amino acid side chains within the transmembrane-spanning helixes of the P2X2 receptorAgonist antagonist interactions at the rapidly desensitizing P2X3 receptorActivation and regulation of purinergic P2X receptor channelsParoxetine suppresses recombinant human P2X7 responsesPharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567.New structure enlivens interest in P2X receptors.Pharmacological properties of the rhesus macaque monkey P2X7 receptor.The microglial ATP-gated ion channel P2X7 as a CNS drug target.Characterization of three diaminopyrimidines as potent and selective antagonists of P2X3 and P2X2/3 receptors with in vivo efficacy in a pain model.Development of a comprehensive set of P2 receptor pharmacological research compoundsDocking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human.The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro.Raft localization of type I Fcε receptor and degranulation of RBL-2H3 cells exposed to decavanadate, a structural model for V2O5.Probenecid directly impairs activation of the canine P2X7 receptor.The P2X7 Receptor.Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors.
P2860
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P2860
Mechanism of action of species-selective P2X(7) receptor antagonists.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Mechanism of action of species-selective P2X
@nl
Mechanism of action of species-selective P2X(7) receptor antagonists.
@en
type
label
Mechanism of action of species-selective P2X
@nl
Mechanism of action of species-selective P2X(7) receptor antagonists.
@en
prefLabel
Mechanism of action of species-selective P2X
@nl
Mechanism of action of species-selective P2X(7) receptor antagonists.
@en
P2093
P2860
P1476
Mechanism of action of species-selective P2X(7) receptor antagonists.
@en
P2093
Anton D Michel
Daryl S Walter
David K Dean
Shilina Roman
Sin-Wei Ng
William C Clay
P2860
P304
P356
10.1111/J.1476-5381.2009.00135.X
P407
P577
2009-03-20T00:00:00Z