Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters
about
The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4.Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal sizeReannotation of the CELO genome characterizes a set of previously unassigned open reading frames and points to novel modes of host interaction in avian adenovirusesCervical cancer isolate PT3, super-permissive for adeno-associated virus replication, over-expresses DNA polymerase delta, PCNA, RFC and RPA.Inhibition of herpes simplex virus type 1 replication by adeno-associated virus rep proteins depends on their combined DNA-binding and ATPase/helicase activities.Adeno-associated virus type 2 rep protein inhibits human papillomavirus type 16 E2 recruitment of the transcriptional coactivator p300.Human adeno-associated virus type 5 is only distantly related to other known primate helper-dependent parvoviruses.Inhibition of PrKX, a novel protein kinase, and the cyclic AMP-dependent protein kinase PKA by the regulatory proteins of adeno-associated virus type 2.Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2.Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein.Adeno-associated virus major Rep78 protein disrupts binding of TATA-binding protein to the p97 promoter of human papillomavirus type 16Mechanism of Rep-mediated adeno-associated virus origin nicking.Amino-terminal domain exchange redirects origin-specific interactions of adeno-associated virus rep78 in vitro.High mobility group chromosomal protein 1 binds to the adeno-associated virus replication protein (Rep) and promotes Rep-mediated site-specific cleavage of DNA, ATPase activity and transcriptional repression.DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsidsA genetic screen identifies a cellular regulator of adeno-associated virus.Adeno-associated virus type 2 Rep78 inhibition of PKA and PRKX: fine mapping and analysis of mechanism.Adeno-associated virus: a key to the human genome?Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRbAdeno-associated virus rep protein-mediated inhibition of transcription of the adenovirus major late promoter in vitro.Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector.Adeno-associated virus type 2 infection activates caspase dependent and independent apoptosis in multiple breast cancer lines but not in normal mammary epithelial cells.The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection.The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter.Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products.The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation.The Rep78 gene product of adeno-associated virus (AAV) self-associates to form a hexameric complex in the presence of AAV ori sequences.Differential suppression of the tumorigenicity of HeLa and SiHa cells by adeno-associated virus.Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus ReplicationIdentification of cellular proteins that interact with the adeno-associated virus rep proteinIdentification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric InterfaceAdeno-associated virus type 2 induces apoptosis in human papillomavirus-infected cell lines but not in normal keratinocytes.Transcriptional analysis of the adeno-associated virus integration site.PKA/PrKX activity is a modulator of AAV/adenovirus interaction.Differential contribution of adeno-associated virus type 2 Rep protein expression and nucleic acid elements to inhibition of adenoviral replication in cis and in trans.Adeno-associated virus Rep represses the human integration site promoter by two pathways that are similar to those required for the regulation of the viral p5 promoter.HPV-16 E1, E2 and E6 each complement the Ad5 helper gene set, increasing rAAV2 and wt AAV2 production.Charged-to-alanine scanning mutagenesis of the N-terminal half of adeno-associated virus type 2 Rep78 protein.Comparative characterization of rep proteins from the helper-dependent adeno-associated virus type 2 and the autonomous goose parvovirus.Adeno-associated virus Rep78 protein interacts with protein kinase A and its homolog PRKX and inhibits CREB-dependent transcriptional activation
P2860
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P2860
Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Mutational analysis of adeno-a ...... ogous and homologous promoters
@en
Mutational analysis of adeno-a ...... gous and homologous promoters.
@nl
type
label
Mutational analysis of adeno-a ...... ogous and homologous promoters
@en
Mutational analysis of adeno-a ...... gous and homologous promoters.
@nl
prefLabel
Mutational analysis of adeno-a ...... ogous and homologous promoters
@en
Mutational analysis of adeno-a ...... gous and homologous promoters.
@nl
P2093
P2860
P1433
P1476
Mutational analysis of adeno-a ...... ogous and homologous promoters
@en
P2093
P2860
P304
P407
P577
1995-09-01T00:00:00Z