Regioselective glucuronidation of tanshinone iia after quinone reduction: identification of human UDP-glucuronosyltransferases, species differences, and interaction potential.
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An NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancerInsight into the pharmacokinetic behavior of tanshinone IIA in the treatment of Crohn's disease: comparative data for tanshinone IIA and its two glucuronidated metabolites in normal and recurrent colitis models after oral administration.PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis.UDP-glucuronosyltransferase 1A compromises intracellular accumulation and anti-cancer effect of tanshinone IIA in human colon cancer cellsMetabolism of kurarinone by human liver microsomes and its effect on cytotoxicity.Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs).Pharmacokinetics and metabolism of jatrorrhizine, a gastric prokinetic drug candidate.
P2860
Q28481620-9A39448A-3224-45FD-BBFB-60AA5FB00C29Q31068601-6E9EF662-9430-4FF1-AC28-FD1CA7A6E3C8Q34184931-C774BBB5-C2C9-425C-9E62-E7AED42B9296Q37309175-734FD575-843E-4B55-85E7-C9B70A4BC0F9Q42820229-09BF7ABA-51F2-458B-A7DA-3BB0F1B9DE44Q50677662-4236CD54-BF40-4E2C-98DC-45D14356D7FAQ51421067-5D1D29C7-C879-4965-92B4-1ADC5908ADC3
P2860
Regioselective glucuronidation of tanshinone iia after quinone reduction: identification of human UDP-glucuronosyltransferases, species differences, and interaction potential.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Regioselective glucuronidation ...... es, and interaction potential.
@en
Regioselective glucuronidation ...... es, and interaction potential.
@nl
type
label
Regioselective glucuronidation ...... es, and interaction potential.
@en
Regioselective glucuronidation ...... es, and interaction potential.
@nl
prefLabel
Regioselective glucuronidation ...... es, and interaction potential.
@en
Regioselective glucuronidation ...... es, and interaction potential.
@nl
P2093
P356
P1476
Regioselective glucuronidation ...... ces, and interaction potential
@en
P2093
Guangji Wang
Qiong Wang
Shan Jiang
Xuanxuan Zhu
Yuxin Wang
P304
P356
10.1124/DMD.109.031864
P577
2010-04-09T00:00:00Z