Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions.

Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions.

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http://www.wikidata.org/entity/Q39902184
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy.Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.A dynamic model of HIV integrase inhibition and drug resistance.Therapeutic strategies underpinning the development of novel techniques for the treatment of HIV infection.Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C.Molecular dynamics approaches estimate the binding energy of HIV-1 integrase inhibitors and correlate with in vitro activity.Computer tools in the discovery of HIV-1 integrase inhibitorsEffect of HIV-1 Subtype C integrase mutations implied using molecular modeling and docking data.A targeted DNA substrate mechanism for the inhibition of HIV-1 integrase by inhibitors with antiretroviral activity.Piecing together the structure of retroviral integrase, an important target in AIDS therapyExamination of halogen substituent effects on HIV-1 integrase inhibitors derived from 2,3-dihydro-6,7-dihydroxy-1H-isoindol-1-ones and 4,5-dihydroxy-1H-isoindole-1,3(2H)-dionesDiketoacid-genre HIV-1 integrase inhibitors containing enantiomeric arylamide functionality.In search of second-generation HIV integrase inhibitors: targeting integration beyond strand transfer.Study on the interactions between diketo-acid inhibitors and prototype foamy virus integrase-DNA complex via molecular docking and comparative molecular dynamics simulation methods.Identification of novel HIV-1 integrase inhibitors using shape-based screening, QSAR, and docking approach.
P2860

Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions.

Item
http://www.wikidata.org/entity/Q39902184
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
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2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
Docking studies on a new human ...... hrough fluorine substitutions.
@en
Docking studies on a new human ...... hrough fluorine substitutions.
@nl
type
label
Docking studies on a new human ...... hrough fluorine substitutions.
@en
Docking studies on a new human ...... hrough fluorine substitutions.
@nl
prefLabel
Docking studies on a new human ...... hrough fluorine substitutions.
@en
Docking studies on a new human ...... hrough fluorine substitutions.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Docking studies on a new human ...... hrough fluorine substitutions.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698