Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer. - Wikidata - awgldk - TriplyDB

Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer.

Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer.

http://www.wikidata.org/entity/Q39908819

about

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells Smart hybrid materials by conjugation of responsive polymers to biomacromolecules.Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers.Neutral polymer micelle carriers with pH-responsive, endosome-releasing activity modulate antigen trafficking to enhance CD8(+) T cell responses.Enhanced Performance of Plasmid DNA Polyplexes Stabilized by a Combination of Core Hydrophobicity and Surface PEGylation Emerging synthetic approaches for protein-polymer conjugations Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy.Synthesis of folate-functionalized RAFT polymers for targeted siRNA delivery.Nanoparticle delivery of a peptide targeting EGFR signaling Intracellular delivery system for antibody-Peptide drug conjugates Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies.RAFT-synthesized graft copolymers that enhance pH-dependent membrane destabilization and protein circulation times Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction.Development of Non-Viral, Trophoblast-Specific Gene Delivery for Placental Therapy.Three-dimensional localization of polymer nanoparticles in cells using ToF-SIMS.Delivery of intracellular-acting biologics in pro-apoptotic therapies.Intracellular delivery and trafficking dynamics of a lymphoma-targeting antibody-polymer conjugate.Ex vivo red blood cell hemolysis assay for the evaluation of pH-responsive endosomolytic agents for cytosolic delivery of biomacromolecular drugs.Balancing cationic and hydrophobic content of PEGylated siRNA polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo Tunable delivery of siRNA from a biodegradable scaffold to promote angiogenesis in vivo.Polymer blend particles with defined compositions for targeting antigen to both class I and II antigen presentation pathways.MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia.Controlling subcellular delivery to optimize therapeutic effect The use of reversible addition fragmentation chain transfer polymerization for drug delivery systems.Combining RAFT radical polymerization and click/highly efficient coupling chemistries: a powerful strategy for the preparation of novel materials.RAFT polymerization and thiol chemistry: a complementary pairing for implementing modern macromolecular design.NF-κB decoy polyplexes decrease P-glycoprotein-mediated multidrug resistance in colorectal cancer cells.Mechanism of Enhanced Cellular Uptake and Cytosolic Retention of MK2 Inhibitory Peptide Nano-polyplexes.Controlled apoptosis by a thermally toggled nanoscale amplifier of cellular uptake.Poly(PS-b-DMA) micelles for reactive oxygen species triggered drug release.Sustained local delivery of siRNA from an injectable scaffold.Macrophage-specific RNA interference targeting via "click", mannosylated polymeric micelles.Matrix Metalloproteinase Responsive, Proximity-activated Polymeric Nanoparticles for siRNA Delivery.Synthesis of statistical copolymers containing multiple functional peptides for nucleic Acid delivery.Dual MMP7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery.Enzyme-Cleavable Polymeric Micelles for the Intracellular Delivery of Proapoptotic Peptides.Covalently Connected Polymer-Protein Nanostructures Fabricated by a Reactive Self-Assembly Approach.Building nanostructures using RAFT polymerization Stimuli-Responsive Polymer Delivery Systems Block copolymer conjugates prepared by sequentially grafting from proteins via RAFT

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P2860

Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer.

http://www.wikidata.org/entity/Q39908819

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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2010年學術文章

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2010年學術文章

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name

Intracellular delivery of a pr ...... hesized endosomolytic polymer.

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Intracellular delivery of a pr ...... hesized endosomolytic polymer.

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type

label

Intracellular delivery of a pr ...... hesized endosomolytic polymer.

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Intracellular delivery of a pr ...... hesized endosomolytic polymer.

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prefLabel

Intracellular delivery of a pr ...... hesized endosomolytic polymer.

@en

Intracellular delivery of a pr ...... hesized endosomolytic polymer.

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Molecular Pharmaceutics

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Intracellular delivery of a pr ...... hesized endosomolytic polymer.

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P2093

Allan S Hoffman

http://www.w3.org/2001/XMLSchema#string

Anthony J Convertine

http://www.w3.org/2001/XMLSchema#string

Craig L Duvall

http://www.w3.org/2001/XMLSchema#string

Danielle S W Benoit

http://www.w3.org/2001/XMLSchema#string

Patrick S Stayton

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P2860

A stapled BID BH3 helix directly binds and activates BAX

A short Nur77-derived peptide converts Bcl-2 from a protector to a killer

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.

Prognostic significance of Bcl-2 protein expression and Bcl-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: first member of a new class of chemotherapeutic agents-drug-polymer conjugates. Cancer Research Campaign Phase I/II Committee

Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions

The Bcl2 family: regulators of the cellular life-or-death switch

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor

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468-476

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scholarly article

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10.1021/MP9002267

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2

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40455240

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19968323

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2849913

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