Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans. - Wikidata - awgldk - TriplyDB

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

http://www.wikidata.org/entity/Q39918678

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Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles DNA polymerase θ (POLQ), double-strand break repair, and cancer Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?Mechanism of suppression of chromosomal instability by DNA polymerase POLQ Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repair C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency Characteristics of de novo structural changes in the human genome.Human DNA polymerase θ grasps the primer terminus to mediate DNA repair Having a direct look: analysis of DNA damage and repair mechanisms by next generation sequencing.Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis Essential role for polymerase specialization in cellular nonhomologous end joining.G4-associated human diseases.The Transcriptional Response to DNA-Double-Strand Breaks in Physcomitrella patens Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining.Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells.Linking DNA polymerase theta structure and function in health and disease Systematic discovery of complex insertions and deletions in human cancers.Construction of a large collection of small genome variations in French dairy and beef breeds using whole-genome sequences.Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement.Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival.Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.Moonlighting at replication forks - a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51.Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers.T-DNA integration in plants results from polymerase-θ-mediated DNA repair.CRISPR/Cas9-Induced Double-Strand Break Repair in Arabidopsis Nonhomologous End-Joining Mutants.Dual loss of human POLQ and LIG4 abolishes random integration.A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans.Expression and Structural Analyses of Human DNA Polymerase θ (POLQ).Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development.Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation.Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.The DNA translocase RAD5A acts independently of the other main DNA repair pathways, and requires both its ATPase and RING domain for activity in Arabidopsis thaliana.A simple answer to complex questions: Caenorhabditis elegans as an experimental model for examining the DNA damage response and disease genes.p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways.A Distinct Class of Chromoanagenesis Events Characterized by Focal Copy Number Gains.Complex Multiple-Nucleotide Substitution Mutations Causing Human Inherited Disease Reveal Novel Insights into the Action of Translesion Synthesis DNA Polymerases.Disclosing the Hidden Structure and Underlying Mutational Mechanism of a Novel Type of Duplication CNV Responsible for Hereditary Multiple Osteochondromas The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells

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Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

http://www.wikidata.org/entity/Q39918678

description

2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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2014年學術文章

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2014年學術文章

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name

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

@en

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

@nl

type

label

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

@en

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

@nl

prefLabel

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

@en

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

@nl

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Genome Research

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Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans

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Robin van Schendel

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Sophie F Roerink

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P2860

The genetics of Caenorhabditis elegans

Mutational processes molding the genomes of 21 breast cancers

Fast and accurate short read alignment with Burrows-Wheeler transform

A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis

The Sequence Alignment/Map format and SAMtools

Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase eta.

Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta.

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

Translesion synthesis by human DNA polymerase eta across thymine glycol lesions

A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders

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954-962

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scholarly article

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10.1101/GR.170431.113

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6

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24

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Marcel Tijsterman

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2014-03-10T00:00:00Z

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260683300

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24614976

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Caenorhabditis elegans

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4032859

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