Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani.
about
Characterization of the DNA-binding domain and identification of the active site residue in the 'Gyr A' half of Leishmania donovani topoisomerase IImAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity.Centromere-associated topoisomerase activity in bloodstream form Trypanosoma bruceiIsobenzofuranone derivatives exhibit antileishmanial effect by inhibiting type II DNA topoisomerase and inducing host response.Identification and characterization of the regions involved in the nuclear translocation of the heterodimeric leishmanial DNA topoisomerase IB.Topoisomerases of kinetoplastid parasites: why so fascinating?Impact of the C-terminal domain of topoisomerase IIalpha on the DNA cleavage activity of the human enzyme.Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discoveryCharacterization of the ATPase activity of topoisomerase II from Leishmania donovani and identification of residues conferring resistance to etoposide.Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani.N-terminal region of the large subunit of Leishmania donovani bisubunit topoisomerase I is involved in DNA relaxation and interaction with the smaller subunit.
P2860
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P2860
Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Functional dissection of the C ...... lagellate Leishmania donovani.
@en
Functional dissection of the C ...... lagellate Leishmania donovani.
@nl
type
label
Functional dissection of the C ...... lagellate Leishmania donovani.
@en
Functional dissection of the C ...... lagellate Leishmania donovani.
@nl
prefLabel
Functional dissection of the C ...... lagellate Leishmania donovani.
@en
Functional dissection of the C ...... lagellate Leishmania donovani.
@nl
P2093
P2860
P356
P1476
Functional dissection of the C ...... lagellate Leishmania donovani.
@en
P2093
Chhabinath Mandal
Hemanta K Majumder
Mandira Mukherjee
Tanushri Sengupta
P2860
P304
P356
10.1093/NAR/GKG727
P577
2003-09-01T00:00:00Z