Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting.
about
Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunctionRAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regionsEfficient integration of transgenes into a defined locus in human embryonic stem cells.Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene.DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair.Analysis of the role of homology arms in gene-targeting vectors in human cellsConstruction and applications of exon-trapping gene-targeting vectors with a novel strategy for negative selection.Improved Gene Targeting through Cell Cycle SynchronizationTargeted Integration of a Super-Exon into the CFTR Locus Leads to Functional Correction of a Cystic Fibrosis Cell Line Model.Suppression of Ku70/80 or Lig4 leads to decreased stable transformation and enhanced homologous recombination in rice.Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications.Use of microarray hybrid capture and next-generation sequencing to identify the anatomy of a transgene.MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineeringPartial loss of interleukin 2 receptor gamma function in pigs provides mechanistic insights for the study of human immunodeficiency syndrome.Mechanistic basis for increased human gene targeting by promoterless vectors-roles of homology arms and Rad54 paralogs.CRISPR/Cas9-mediated somatic and germline gene correction to restore hemostasis in hemophilia B mice.Biallelic Gene Targeting in Rice.Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA.Dual loss of human POLQ and LIG4 abolishes random integration.Unique molecular mechanisms for maintenance and alteration of genetic information in the budding yeast Saccharomyces cerevisiae.Nonviral gene targeting at rDNA locus of human mesenchymal stem cells.
P2860
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P2860
Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Impact of non-homologous end-j ...... plications for gene targeting.
@en
Impact of non-homologous end-j ...... plications for gene targeting.
@nl
type
label
Impact of non-homologous end-j ...... plications for gene targeting.
@en
Impact of non-homologous end-j ...... plications for gene targeting.
@nl
prefLabel
Impact of non-homologous end-j ...... plications for gene targeting.
@en
Impact of non-homologous end-j ...... plications for gene targeting.
@nl
P2093
P2860
P356
P1476
Impact of non-homologous end-j ...... mplications for gene targeting
@en
P2093
Ayako Ishii
Hideki Koyama
Noritaka Adachi
Susumu Iiizumi
Yasuyuki Ishii
Yuichi Chikaraishi
P2860
P304
P356
10.1093/NAR/GKN649
P50
P577
2008-10-03T00:00:00Z