The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells.
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Hitting the brakes: targeting microtubule motors in cancerDNA damage associated with mitosis and cytokinesis failureBasic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules.Quantitative assessment of chromosome instability induced through chemical disruption of mitotic progressionThe Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitroIntravital FRET imaging of tumor cell viability and mitosis during chemotherapyP38 mitogen-activated protein kinase activity is required during mitosis for timely satisfaction of the mitotic checkpoint but not for the fidelity of chromosome segregation.Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis.The microtubule poison vinorelbine kills cells independently of mitotic arrest and targets cells lacking the APC tumour suppressor more effectively.A novel synthetic 1,3-phenyl bis-thiourea compound targets microtubule polymerization to cause cancer cell death.A protein-RNA specificity code enables targeted activation of an endogenous human transcriptRolled-up functionalized nanomembranes as three-dimensional cavities for single cell studies.Caspase-3-mediated degradation of condensin Cap-H regulates mitotic cell deathKalanchoe tubiflora extract inhibits cell proliferation by affecting the mitotic apparatusCaspase activity is not required for the mitotic checkpoint or mitotic slippage in human cells.Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint.Killing cells by targeting mitosisHaspin inhibitors reveal centromeric functions of Aurora B in chromosome segregationProbing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524.Mechanisms of chromosomal instability.Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachmentsElevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.Phosphorylation of DYNLT1 at serine 82 regulates microtubule stability and mitochondrial permeabilization in hypoxia.Mitosis in vertebrates: the G2/M and M/A transitions and their associated checkpoints.Prevention and correction mechanisms behind anaphase synchrony: implications for the genesis of aneuploidy.Mitosis as an anti-cancer target.Centrosome clustering and chromosomal (in)stability: a matter of life and death.Mitosis as an anti-cancer drug target.Belinostat and vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma.Microtubule-based force generation.Apparent diffusive motion of centrin foci in living cells: implications for diffusion-based motion in centriole duplication.Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.Proteins required for centrosome clustering in cancer cells.Modeling Cancer Cell Growth Dynamics In vitro in Response to Antimitotic Drug TreatmentGenome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptationMelanoma associated antigen (MAGE)-A3 promotes cell proliferation and chemotherapeutic drug resistance in gastric cancer.MYC-Induced miR-203b-3p and miR-203a-3p Control Bcl-xL Expression and Paclitaxel Sensitivity in Tumor Cells
P2860
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P2860
The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The ability to survive mitosis ...... and cancer (U2OS, HeLa) cells.
@en
The ability to survive mitosis ...... and cancer (U2OS, HeLa) cells.
@nl
type
label
The ability to survive mitosis ...... and cancer (U2OS, HeLa) cells.
@en
The ability to survive mitosis ...... and cancer (U2OS, HeLa) cells.
@nl
prefLabel
The ability to survive mitosis ...... and cancer (U2OS, HeLa) cells.
@en
The ability to survive mitosis ...... and cancer (U2OS, HeLa) cells.
@nl
P2860
P356
P1433
P1476
The ability to survive mitosis ...... and cancer (U2OS, HeLa) cells.
@en
P2093
Conly L Rieder
Daniela A Brito
P2860
P304
P356
10.1002/CM.20316
P577
2009-08-01T00:00:00Z