Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein.
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Antiviral perspectives for chikungunya virusMechanism and significance of cell type-dependent neutralization of flavivirusesEnvelope glycoprotein of arenavirusesDNA vaccine initiates replication of live attenuated chikungunya virus in vitro and elicits protective immune response in miceResidue 82 of the Chikungunya virus E2 attachment protein modulates viral dissemination and arthritis in miceLow temperature-dependent salmonid alphavirus glycoprotein processing and recombinant virus-like particle formationNext generation sequencing of DNA-launched Chikungunya vaccine virus.A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primatesEarly neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells.Replication cycle of chikungunya: a re-emerging arbovirus.A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2.An arthropod enzyme, Dfurin1, and a vertebrate furin homolog display distinct cleavage site sequence preferences for a shared viral proprotein substrateInhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expressionEffective chikungunya virus-like particle vaccine produced in insect cells.A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritisInduction of cytopathogenicity in human glioblastoma cells by chikungunya virus.Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.Group X secreted phospholipase A2 proenzyme is matured by a furin-like proprotein convertase and releases arachidonic acid inside of human HEK293 cells.Host cell proteases: Critical determinants of coronavirus tropism and pathogenesisIdentification of potent and compartment-selective small molecule furin inhibitors using cell-based assays.Kinetic characterization of trans-proteolytic activity of Chikungunya virus capsid protease and development of a FRET-based HTS assay.Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder.Longitudinal analysis of the human antibody response to Chikungunya virus infection: implications for serodiagnosis and vaccine developmentOn the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications.Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseasesEffectiveness of chloroquine and inflammatory cytokine response in patients with early persistent musculoskeletal pain and arthritis following chikungunya virus infection.Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin.The cell biology of Chikungunya virus infection.Antiviral Strategies Against Chikungunya Virus.Effects of the prosegment and pH on the activity of PCSK9: evidence for additional processing events.Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.A compendium of small molecule direct-acting and host-targeting inhibitors as therapies against alphaviruses.The proprotein convertase PC7: unique zymogen activation and trafficking pathways.Proprotein convertase PC7 enhances the activation of the EGF receptor pathway through processing of the EGF precursor.Complex antigen presentation pathway for an HLA-A*0201-restricted epitope from Chikungunya 6K protein.Phosphoproteomic analysis reveals Smad protein family activation following Rift Valley fever virus infection.My road to Damascus: how I converted to the prohormone theory and the proprotein convertases.Furin inhibitor D6R suppresses epithelial-mesenchymal transition in SW1990 and PaTu8988 cells via the Hippo-YAP signaling pathway.Current Strategies for Inhibition of Chikungunya Infection.
P2860
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P2860
Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Inhibition of Chikungunya viru ...... f the E2 surface glycoprotein.
@en
Inhibition of Chikungunya viru ...... f the E2 surface glycoprotein.
@nl
type
label
Inhibition of Chikungunya viru ...... f the E2 surface glycoprotein.
@en
Inhibition of Chikungunya viru ...... f the E2 surface glycoprotein.
@nl
prefLabel
Inhibition of Chikungunya viru ...... f the E2 surface glycoprotein.
@en
Inhibition of Chikungunya viru ...... f the E2 surface glycoprotein.
@nl
P2093
P2860
P50
P356
P1476
Inhibition of Chikungunya viru ...... f the E2 surface glycoprotein.
@en
P2093
Ajoy Basak
Josée Hamelin
Kamel Mamchaoui
Marianne Lucas-Hourani
Menogh Valentine
Michel Chrétien
Simona Ozden
Suzanne Benjannet
P2860
P304
21899-21908
P356
10.1074/JBC.M802444200
P407
P50
P5008
P577
2008-06-17T00:00:00Z