The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
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Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice.Is there a link between proprotein convertase PC7 activity and human lipid homeostasis?Proprotein convertases process Pmel17 during secretion.Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.The Golgi apparatus regulates cGMP-dependent protein kinase I compartmentation and proteolysis.PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation.Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder.Opposite roles of furin and PC5A in N-cadherin processing.Proprotein convertases play an important role in regulating PKGI endoproteolytic cleavage and nuclear transport.Proprotein convertase subtilisin/kexin type 3 promotes adipose tissue-driven macrophage chemotaxis and is increased in obesity.Arrivals and departures at the plasma membrane: direct and indirect transport routes.The Processed Amino-Terminal Fragment of Human TLR7 Acts as a Chaperone To Direct Human TLR7 into Endosomes.Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes.Internalization of proprotein convertase PC7 from plasma membrane is mediated by a novel motif.Enhanced Proteolytic Processing of Recombinant Human Coagulation Factor VIII B-Domain Variants by Recombinant Furins.Loss- and gain-of-function PCSK9 variants: cleavage specificity, dominant negative effects, and low density lipoprotein receptor (LDLR) degradationProprotein convertase PC7 enhances the activation of the EGF receptor pathway through processing of the EGF precursor.Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis
P2860
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P2860
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
@en
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
@nl
type
label
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
@en
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
@nl
prefLabel
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
@en
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
@nl
P2093
P2860
P356
P1476
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
@en
P2093
Estelle Rousselet
Josée Hamelin
Maryssa Canuel
Suzanne Benjannet
P2860
P304
P356
10.1074/JBC.M110.192344
P407
P577
2010-11-12T00:00:00Z