Selection of a subpopulation with fewer DNA topoisomerase II alpha gene copies in a doxorubicin-resistant cell line panel.
about
Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activitiesTopoisomerase IIalpha gene (TOP2A) amplification and deletion in cancer--more common than anticipatedUse of a rapid throughput in vivo screen to investigate inhibitors of eukaryotic topoisomerase II enzymesAlteration of topoisomerase II-alpha gene in human breast cancer: association with responsiveness to anthracycline-based chemotherapy.Assessment of Topoisomerase II α status in breast cancer by quantitative PCR, gene expression microarrays, immunohistochemistry, and fluorescence in situ hybridization.Novel molecular markers of malignancy in histologically normal and benign breastHER-2/neu and topoisomerase IIalpha in breast cancer.Topoisomerase IIalpha in Wilms' tumour: gene alterations and immunoexpression.Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer.Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification.DNA topoisomerase IIalpha expression and the response toprimary chemotherapy in breast cancer.Facts and controversies in the use of trastuzumab in the adjuvant setting.HER2/neu, Topoisomerase 2a, Estrogen and Progesterone Receptors: Discordance between Primary Breast Cancer and Metastatic Axillary Lymph Node in Expression and Amplification Characteristics.Chromosomal and genetic alterations of 7,12-dimethylbenz[a]anthracene-induced melanoma from TP-ras transgenic mice.Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.Differential expression of DNA topoisomerase II alpha and -beta in P-gp and MRP-negative VM26, mAMSA and mitoxantrone-resistant sublines of the human SCLC cell line GLC4.Enhanced sensitivity to tumor necrosis factor-alpha in doxorubicin-resistant tumor cell lines due to down-regulated c-erbB2.Dual-colour CISH is a reliable alternative to FISH for assessment of topoisomerase 2-alpha amplification in breast carcinomas.Role of proliferation in HER2 status predicted response to doxorubicin.High expression of Bcl-2 predicts poor outcome in diffuse large B-cell lymphoma patients with low international prognostic index receiving R-CHOP chemotherapy.High topoisomerase IIalpha expression associates with high proliferation rate and and poor prognosis in oligodendrogliomas.Topoisomerase II-alpha gene deletion is not frequent as its amplification in breast cancer.Cancer du sein métastatique
P2860
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P2860
Selection of a subpopulation with fewer DNA topoisomerase II alpha gene copies in a doxorubicin-resistant cell line panel.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Selection of a subpopulation w ...... cin-resistant cell line panel.
@en
Selection of a subpopulation w ...... cin-resistant cell line panel.
@nl
type
label
Selection of a subpopulation w ...... cin-resistant cell line panel.
@en
Selection of a subpopulation w ...... cin-resistant cell line panel.
@nl
prefLabel
Selection of a subpopulation w ...... cin-resistant cell line panel.
@en
Selection of a subpopulation w ...... cin-resistant cell line panel.
@nl
P2093
P2860
P356
P1476
Selection of a subpopulation w ...... cin-resistant cell line panel.
@en
P2093
de Vries EG
P2860
P2888
P304
P356
10.1038/BJC.1996.393
P407
P577
1996-08-01T00:00:00Z
P5875
P6179
1021029259