Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively.
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Structure and function of type II DNA topoisomerasesEvaluation of EML4-ALK fusion proteins in non-small cell lung cancer using small molecule inhibitors(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerasesIsolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24Collision of Trapped Topoisomerase 2 with Transcription and Replication: Generation and Repair of DNA Double-Strand Breaks with 5' AdductsEnhanced etoposide sensitivity following adenovirus-mediated human topoisomerase IIalpha gene transfer is independent of topoisomerase IIbetaReplication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposideThe use of divalent metal ions by type II topoisomerases.The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathwayHistone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatinNurr1 regulates Top IIβ and functions in axon genesis of mesencephalic dopaminergic neuronsFunctional interaction between human topoisomerase IIalpha and retinoblastoma protein.The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues.Tyrosine 656 in topoisomerase IIβ is important for the catalytic activity of the enzyme: Identification based on artifactual +80-Da modification at this siteDNA topoisomerase II, genotoxicity, and cancerThe DNA cleavage reaction of topoisomerase II: wolf in sheep's clothingImmunohistochemical study of topoisomerase II-alpha expression in primary ductal carcinoma of the breast.Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity.The function of DNA topoisomerase IIβ in neuronal developmentThe α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells.Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II.Selection of a subpopulation with fewer DNA topoisomerase II alpha gene copies in a doxorubicin-resistant cell line panel.Differential expression of DNA topoisomerase II alpha and -beta in P-gp and MRP-negative VM26, mAMSA and mitoxantrone-resistant sublines of the human SCLC cell line GLC4.C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.Multilevel therapeutic targeting by topoisomerase inhibitors.Expression of topoisomerase II alpha and beta in an adenocarcinoma cell line carrying amplified topoisomerase II alpha and retinoic acid receptor alpha genes.Novel selection and genetic characterisation of an etoposide-resistant human leukaemic CCRF-CEM cell line.Characterization of the human topoisomerase IIbeta (TOP2B) promoter activity: essential roles of the nuclear factor-Y (NF-Y)- and specificity protein-1 (Sp1)-binding sites.Proliferation-associated nuclear antigen Ki-S1 is identical with topoisomerase II alpha. Delineation of a carboxy-terminal epitope with peptide antibodies.Detection of the Epstein-Barr virus and DNA-topoisomerase II- α in recurrent and nonrecurrent giant cell lesion of the jawbonesCORRELATIONSHIP OF CATHEPSIN D AND TOPOISOMERASE II ALPHA WITH NUCLEAR GRADING IN BREAST CANCERS.Relationship between expression of topoisomerase II isoforms and intrinsic sensitivity to topoisomerase II inhibitors in breast cancer cell lines.TOP2B: The First Thirty Years
P2860
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P2860
Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively.
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@ast
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@en
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@nl
type
label
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@ast
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@en
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@nl
prefLabel
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@ast
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@en
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@nl
P2093
P1433
P1476
Topoisomerase II alpha and top ...... osomes 17 and 3, respectively.
@en
P2093
Mirabelli CK
P304
P407
P577
1992-01-01T00:00:00Z