Novel HeLa topoisomerase II is the II beta isoform: complete coding sequence and homology with other type II topoisomerases.
about
Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalphaA DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulatorStructure and function of type II DNA topoisomerasesCollision of Trapped Topoisomerase 2 with Transcription and Replication: Generation and Repair of DNA Double-Strand Breaks with 5' AdductsThe Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA CleavageEnhanced etoposide sensitivity following adenovirus-mediated human topoisomerase IIalpha gene transfer is independent of topoisomerase IIbetaReplication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposideSCP2: a major protein component of the axial elements of synaptonemal complexes of the ratCasein kinase II catalyzes a mitotic phosphorylation on threonine 1342 of human DNA topoisomerase IIalpha, which is recognized by the 3F3/2 phosphoepitope antibody.Recovery of the poisoned topoisomerase II for DNA religation: coordinated motion of the cleavage core revealed with the microsecond atomistic simulation.Actions of heparin that may affect the malignant process.p53 regulates the minimal promoter of the human topoisomerase IIalpha gene.Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.All tangled up: how cells direct, manage and exploit topoisomerase function.Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.Topoisomerase assaysDifferential expression of the topoisomerase II alpha and beta genes in human breast cancers.The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues.Restoration of topoisomerase 2 function by complementation of defective monomers in DrosophilaTyrosine 656 in topoisomerase IIβ is important for the catalytic activity of the enzyme: Identification based on artifactual +80-Da modification at this siteHU-331: a cannabinoid quinone, with uncommon cytotoxic properties and low toxicity.Bimodal recognition of DNA geometry by human topoisomerase II alpha: preferential relaxation of positively supercoiled DNA requires elements in the C-terminal domainTransient dsDNA breaks during pre-replication complex assembly.Phenanthriplatin Acts As a Covalent Poison of Topoisomerase II Cleavage Complexes.Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.The function of DNA topoisomerase IIβ in neuronal developmentRole of topoisomerase IIbeta in the expression of developmentally regulated genes.Regulation of the human topoisomerase IIalpha gene promoter in confluence-arrested cells.DNA topoisomerase-directed anticancerous alkaloids: ADMET-based screening, molecular docking, and dynamics simulation.Detection of human topoisomerase II alpha in cell lines and tissues: characterization of five novel monoclonal antibodies.Pathways of cardiac toxicity: comparison between chemotherapeutic drugs doxorubicin and mitoxantrone.Sequences of conserved region in the A subunit of DNA gyrase from nine species of the genus Mycobacterium: phylogenetic analysis and implication for intrinsic susceptibility to quinolones.Selection of a subpopulation with fewer DNA topoisomerase II alpha gene copies in a doxorubicin-resistant cell line panel.Differential expression of DNA topoisomerase II alpha and -beta in P-gp and MRP-negative VM26, mAMSA and mitoxantrone-resistant sublines of the human SCLC cell line GLC4.C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.Expression of drug resistance genes in VP-16 and mAMSA-selected human carcinoma cells.Molecular cloning and expression of the Candida albicans TOP2 gene allows study of fungal DNA topoisomerase II inhibitors in yeast.Inhibition of DNA Topoisomerase Type IIα (TOP2A) by Mitoxantrone and Its Halogenated Derivatives: A Combined Density Functional and Molecular Docking Study.Relationship between expression of topoisomerase II isoforms and intrinsic sensitivity to topoisomerase II inhibitors in breast cancer cell lines.
P2860
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P2860
Novel HeLa topoisomerase II is the II beta isoform: complete coding sequence and homology with other type II topoisomerases.
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@ast
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@en
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@nl
type
label
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@ast
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@en
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@nl
prefLabel
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@ast
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@en
Novel HeLa topoisomerase II is ...... other type II topoisomerases.
@nl
P2093
P1476
Novel HeLa topoisomerase II is ...... h other type II topoisomerases
@en
P2093
P304
P356
10.1016/0167-4781(93)90215-Y
P407
P577
1993-03-01T00:00:00Z